Basics of Mouse Genetics
This MiniCourse is self-paced and takes 3 to 5 hours to complete. At the end of the MiniCourse, you will be able define the unique advantages of using mice in genetic and genomic research. You will receive a certificate and digital badge for completing the MiniCourse. In order to claim a certificate or badge for this MiniCourse, you must go through the Core Content module and take the self-review quiz (scoring at least 70%).
The following topics will be discussed:
- Mendelian genetics
- Origins of laboratory mice and inbred mouse strains
- Breeding schemes and classical genetic resources
- Genetic diversity in the Collaborative Cross (CC) and Diversity Outbred (DO) mice
- Overview of the basic inbred strain experiment
- Basic genetics of the mouse
- Mouse strain nomenclature
- Targeted alleles
By the end of the MiniCourse, you will be able to:
- Discover how Mendelian genetics led to the inbred strain experiment
- Define the inbred strain and its significance to genetics
- Identify mouse mating schemes including incross, outcross, intercross, and backcross
- Describe classic genetic resources including consomics, congenics, recombinant inbreds, and coisogenics
- Define new genetically diverse mouse models; the Collaborative Cross and the Diversity Outbred
- Analyze the process for the basic inbred strain experiment
- Properly interpret nomenclature for various mouse model systems
- Identify the advantage of using genetically engineered mice for genetic studies
This MiniCourse is designed to meet the needs of graduate and post-doctoral students, research assistants, advanced undergraduate students, and advanced animal care technicians.
About our Education Offerings
Founded in 1929, The Jackson Laboratory (JAX) is an independent, nonprofit biomedical research institution with more than 2,200 employees who are passionate about our mission: to discover precise genomic solutions for disease and to empower the global biomedical community in the shared quest to improve human health.
While we are not an accredited higher education institution, we offer a variety of education programs — including our non-credit bearing MiniCourses and Certificates — designed to educate current and future scientists and to provide critical resources, data, tools, and services to researchers worldwide.
MiniCourses are created and reviewed by multiple JAX faculty, scientists, educators, and other experts, and include interactive content based on the live lectures delivered in our on-campus Courses, Conferences, and Workshops.
MiniCourses are available to learners individually and in topical Certificate Program collections, which are organized around both foundational content and the research areas in which The Jackson Laboratory has earned a reputation for scientific leadership and excellence.
Hardware and Software Requirements
- Audio speakers or headphones
- Screen resolution of 800X600 or higher
- Adobe Reader 5.0 or higher
- 1GB of RAM
- 2GHz processor
Should you have questions regarding the content of the MiniCourse or if you need technical support, please email Online and Digital Education at The Jackson Laboratory.