Understanding the C57BL/6J Mouse Model: From Genetic Origins to Research Applications
This webinar highlights many aspects of the C57BL/6J strain, one of the most widely utilized inbred models in biomedical research.
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Cells and Tissues
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Cre Lox Breeding for Beginners, Part 1
Simply put, the Cre/lox system rocks. It is one of the most powerful tools in the mouse geneticist’s toolbox. Why? Well, it enables them to generate tissue-specific and inducible knockouts and...
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Cre Lox Breeding for Beginners, Part 2
In a previous post I discussed breeding Cre/lox mice to generate tissue-specific and inducible conditional knockout mouse strains. I would now like to continue the discussion of breeding Cre/lox...
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Insourcing or Outsourcing your Breeding Projects: Considerations and Advice for Making this Critical Decision
Many commercial and academic researchers have access to a vivarium and have not seriously considered using outside resources. Rising model complexity, tighter budgets, and shrinking vivarium...
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Supporting Reproducibility & the 3R’s with Effective Mouse Colony Management
In this webinar, we share advice on maintaining mouse colonies that align with the 3Rs principles: replacement, reduction, and refinement.
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JAX Resources for the Management of Transgenic Mice
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Using Cre-lox Technology in Mouse Modeling
In this webinar, we discuss cre-lox technology, a widely used and sophisticated tool to create general knockouts, conditional knockouts, and reporter strains.
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JAX Tech Talk Episode 65: Let’s Talk Tools to Consider after Generating a New Mouse Model (Jul. 11, 2023)
JAX technical information scientists Neeraj Tiwari and Peter Kelmenson discuss JAX research services including model selection, model generation and breeding.
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JAX Tech Talk Episode 61: Let’s Talk Genotyping 2.0 – Overview of Questions and Misconceptions (Dec. 6, 2022)
December 6, 2022 In this episode of JAX Tech Talk, we discuss genotyping topics and misconceptions people have about our assays.
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2022 AALAS P231 Initial Validation and Ongoing Quality Control of Process Equipment
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2022 AALAS P31 Practicing the 3R's
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2022 AALAS P52 How the IACUC Worked with Business Partners to Develop a Safety Review Process to Reduce Regulatory Burden
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Cryorecovery
JAX successfully cryorecovers over 2,500 strains each year for researchers worldwide - including genetically complex and fragile strains.
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Speed Congenics
Using Speed Congenics, we can take your strain and produce genetically well-defined congenic mice of high health status in half the time of traditional backcrossing.
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Breeding Services
Our Breeding Services makes managing your mouse colonies easy and affordable. We will make sure you get the mice you need when you need them.
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Cryopreservation
JAX Cryopreservation offers fast and reliable methods for archiving embryos and sperm so you can feel assured about the safety of your strains and save space for the strains you need now.
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Genome Scanning
Using a small sample of DNA, JAX can provide an estimate of the genetic contributions from two strains within a given mouse.
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Rederivation
Pathogen outbreaks, relocating your laboratory, etc., can jeopardize the size or continuity of your colony. Our rederivation service can help reestablish your strain(s) at the highest health status.
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Disaster Preparedness
For over 90 years JAX has been helping researchers reliably and cost-effectively mitigate risk by preserving strains through our reproductive services.
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Refinements Of JVC
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