Cells and Tissues

Tools with a Mission: Using Disease Models to Find a Treatment for PURA Syndrome

This webinar explores the urgent need for innovative models and highlights JAX’s development of iPSC lines to advance understanding of PURA syndrome and enable drug discovery.

JAX Tech Talk Episode 68: Let’s Talk iPSC Disease Models as a Tool in Drug Discovery (Nov. 7, 2023)

During this JAX Tech Talk, Dr. Steven Rodriguez, Lab Head of the Rare & Neurological Diseases Therapeutic Area at Sanofi, discusses how his group uses iPSC models to understand disease biology.

JAX Tech Talk Episode 59: Let’s Talk iPSCs and Their Value in Tackling Neurodegenerative Diseases (Sep. 20, 2022)

Dr. Mark Cookson talks about the unique aspects of the collection of human isogenic iPSC lines and how it can benefit the wider scientific community in their shared quest to understand and fight ADRD.

MiceTech Talk Episode 25: Let's Talk Cancer Modeling with PDX Mice (Dec. 1, 2020)

December 1, 2020 - In this episode, we will be discussing what PDX models are, why they are considered more translatable, and examples of preclinical cancer studies conducted at JAX.

Comparing Effects of Irradiation & Mam. Fat Pad Implantation on the Growth of Non-breast PDX Models

Cre-lox Basics: Cre-lox Technology in Mouse Modeling

Watch this video to learn about the principles of the technology, basic research applications and how to access the world’s largest collection of Cre-lox strains.

Optimal Design of PDX to Study Cancer Pathogenesis and Responses to Therapy

During this presentation, Dr. Bankert discusses the optimal design of patient derived xenografts (PDX) to study cancer pathogenesis and responses to therapy.