JAX Envision™ · Application Note - Continuous Digital Phenotyping Reveals Treatment-Sensitive Changes in a Neurodevelopmental Model
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Reference Guide to Mouse Models of Spinal Muscular Atrophy
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Timed Pregnant Mice: Practical Tips for Improving Success
Need embryos or pups at a specific developmental stage? Timed matings are one of the most effective tools for generating age-matched cohorts and planning experiments with greater confidence....
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Designing Smarter ALS Studies: Best Practices with JAX Mouse Models
In this webinar, you will learn best practices for study design using JAX ALS models to support your ALS research.
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Understanding Passage Limits and iPSC Cell Line Consistency
How many times can an iPSC cell line be split and expanded?While iPSCs can be expanded in culture, extended passaging can introduce changes that affect the reliability and reproducibility of...
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iPSCs: Modeling Disease and Advancing Therapies
Explore how induced pluripotent stem cells (iPSCs) are transforming human health across three powerful frontiers: disease research, drug discovery, and cell replacement therapy
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Stem Cells: An Introduction to iPSC Biology
Learn the basics of stem cell biology, with a particular focus on induced pluripotent stem cells, or iPSCs.
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Modeling Differential Patient Responses to B Cell Elimination with S15-DKO
Learn how S15-DKO mice can be used to evaluate tri-specific killer engagers (TriKEs) in the settings of lupus and B cell lymphoma.
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Mouse Models that Bridge the Gap in Immunotherapy Discovery
Immunotherapy is an effective way to fight cancer using the body’s own immune system. From basic research to drug discovery, in vivo modeling has become the cornerstone of immunotherapy...
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What is a Humanized Mouse? FAQs about models for immunology, immuno-oncology, and pharmacokinetics.
What is a humanized mouse model?A humanized mouse refers to a mouse that carries some aspect(s) of human biology. For instance, “humanized” could refer to a mouse expressing a human gene...
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Mouse Models Shaping Antiviral Vaccine Development
This webinar explores how diverse mouse models have been used to develop and refine antiviral vaccines.
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Optimizing Experimental Design Using Aged Mouse Models
This webinar addresses critical elements of experimental design that support the efficiency, rigor, and reproducibility of aging studies.
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Understanding the C57BL/6J Mouse Model: From Genetic Origins to Research Applications
This webinar highlights many aspects of the C57BL/6J strain, one of the most widely utilized inbred models in biomedical research.
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ABCs of Antibody Discovery: Leveraging Biological Foundations and Modern Platforms
This webinar discusses the shift toward antibody therapeutics as a more precise and targeted alternative to traditional therapies.
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Envision 5.0 - A Platform Built for Home Cage Research
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Diet-induced Obese Tg32 (hFcRN) : a New Platform for PK Analysis of Anti-obesity Peptide-Fc Based and Antibody Therapeutics
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Advancing Translational Relevance in Preclinical Mouse Models for Alzheimer’s Disease
Watch this webinar for guidance on the informed selection of in vivo mouse models for the preclinical evaluation of therapeutic candidates for Alzheimer’s disease.
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An Introduction to iPSCs: Applications, Models, and Best Practices
In this webinar, we’ll cover the basics of iPSCs, showcase real-world research applications, and discuss the biological questions these models help answer.
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An Advanced PBMC-Humanized NSG-S15-DKO Mouse Model for Comprehensive Evaluation of Immunotherapeutics
What You'll Learn:PBMC models enable in vivo human immune system studiesDelayed GvHD supports longer, more flexible study windowsNSG-S15-DKO shows:Enhanced multi-lineage engraftment (T, NK,...
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S15-DKO: New Platform for Engraftment of Human PBMC Supporting Multilineage Immune Cells, Low GvHD
Learn about the S15‑DKO strain (NSG-NSG‑MHC I/II DKO × NSG‑SGM3‑IL15), which supports broader human immune cell engraftment (T, B/plasma, NK, cDC, macrophages, γδ T cells) without acute xGvHD.
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