Understanding the C57BL/6J Mouse Model: From Genetic Origins to Research Applications
This webinar highlights many aspects of the C57BL/6J strain, one of the most widely utilized inbred models in biomedical research.
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ABCs of Antibody Discovery: Leveraging Biological Foundations and Modern Platforms
This webinar discusses the shift toward antibody therapeutics as a more precise and targeted alternative to traditional therapies.
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Envision 5.0_A Platform Built for Home Cage Research
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Diet-induced Obese Tg32 (hFcRN) : a New Platform for PK Analysis of Anti-obesity Peptide-Fc Based and Antibody Therapeutics
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Advancing Translational Relevance in Preclinical Mouse Models for Alzheimer’s Disease
Watch this webinar for guidance on the informed selection of in vivo mouse models for the preclinical evaluation of therapeutic candidates for Alzheimer’s disease.
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An Introduction to iPSCs: Applications, Models, and Best Practices
In this webinar, we’ll cover the basics of iPSCs, showcase real-world research applications, and discuss the biological questions these models help answer.
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An Advanced PBMC-Humanized NSG-S15-DKO Mouse Model for Comprehensive Evaluation of Immunotherapeutics
What You'll Learn:PBMC models enable in vivo human immune system studiesDelayed GvHD supports longer, more flexible study windowsNSG-S15-DKO shows:Enhanced multi-lineage engraftment (T, NK,...
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S15-DKO: New Platform for Engraftment of Human PBMC Supporting Multilineage Immune Cells, Low GvHD
Learn about the S15‑DKO strain (NSG-NSG‑MHC I/II DKO × NSG‑SGM3‑IL15), which supports broader human immune cell engraftment (T, B/plasma, NK, cDC, macrophages, γδ T cells) without acute xGvHD.
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The JAX-NYSCF Global Stem Cell Array®️
Automated platform to generate high-quality induced iPSC lines and differentiate them into diverse, disease-relevant cell types. Advanced capabilities for efficient, reproducible research.
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Home Sweet Home: Leveraging Continuous Home-Cage Monitoring to Improve Science and Animal Welfare
Learn how the Behavioral Phenotyping Core at Seattle Children’s Research Institute expanded its capabilities with the integration of the Allentown Discovery IVC Rack powered by The Jackson Laboratory.
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Highly Advanced Immune Humanized Platforms for Immuno-Oncology Drug Discovery
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Partner with JAX-NYSCF
Learn more about the JAX-NYSCF partnership to accelerate cures for the major diseases of our time through stem cell research, from large iPSC cohorts for specific disease areas to developing...
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New JAX NSG portfolio strains support development of human NK cells in oncology models
IntroductionNatural killer (NK) cells occupy an intriguing niche between adaptive and innate immunity. Like cytotoxic T lymphocytes, they can recognize and kill infected or malignant cells and...
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Powering Discovery with JAX iPSC Models
View highlights and comparison of JAX genetically engineered isogenic iPSC and donor-derived, disease-specific iPSC lines.
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Comparing Mouse Models for Metabolic Disease: Diabetes, Obesity, and MASH
Watch this webinar to learn how different mouse models capture different facets of human metabolic disease.
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Cre Lox Breeding for Beginners, Part 1
Simply put, the Cre/lox system rocks. It is one of the most powerful tools in the mouse geneticist’s toolbox. Why? Well, it enables them to generate tissue-specific and inducible knockouts and...
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Cre Lox Breeding for Beginners, Part 2
In a previous post I discussed breeding Cre/lox mice to generate tissue-specific and inducible conditional knockout mouse strains. I would now like to continue the discussion of breeding Cre/lox...
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A Third-Generation Immune Humanized Mouse Model for the Study of Novel Immuno-Oncology Approaches
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NSGF6T, A Humanized Mouse Model Recapitulating Key Features of Psoriasis for Translational Research
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A New and Differentiated Transgenic Platform for Rapid Generation of Developable Human Therapeutic Antibodies
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