Optimizing Experimental Design Using Aged Mouse Models
This webinar addresses critical elements of experimental design that support the efficiency, rigor, and reproducibility of aging studies.
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Neurobiology
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Advancing Translational Relevance in Preclinical Mouse Models for Alzheimer’s Disease
Watch this webinar for guidance on the informed selection of in vivo mouse models for the preclinical evaluation of therapeutic candidates for Alzheimer’s disease.
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The JAX-NYSCF Global Stem Cell Array®️
Automated platform to generate high-quality induced iPSC lines and differentiate them into diverse, disease-relevant cell types. Advanced capabilities for efficient, reproducible research.
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Home Sweet Home: Leveraging Continuous Home-Cage Monitoring to Improve Science and Animal Welfare
Learn how the Behavioral Phenotyping Core at Seattle Children’s Research Institute expanded its capabilities with the integration of the Allentown Discovery IVC Rack powered by The Jackson Laboratory.
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The Hallmarks of Aging – Key Mechanisms and Models in Neurobiology
Introduction: The History of “Hallmarks” in Biological ResearchLife science researchers worldwide are familiar with the publication series “The Hallmarks of Cancer”, initially laid out by Hanahan...
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JAX Mouse Models of Late-Onset Alzheimer's Disease (LOAD)
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Partner with JAX-NYSCF
Learn more about the JAX-NYSCF partnership to accelerate cures for the major diseases of our time through stem cell research, from large iPSC cohorts for specific disease areas to developing...
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Powering Discovery with JAX iPSC Models
View highlights and comparison of JAX genetically engineered isogenic iPSC and donor-derived, disease-specific iPSC lines.
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Preclinical Neurobiology Services Booklet
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Gene Replacement Mouse Models For Neurodegenerative Diseases
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Open Access to an Improved Preclinical Mouse Model of Familial Alzheimer’s Disease
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Leveraging Biomarkers to Track ALS Progression in Mouse Models for Drug Discovery
Watch this webinar to learn how JAX is leveraging biomarkers—measurable indicators of disease presence, progression, and treatment response—in ALS mouse models.
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Overcoming Challenges in Preclinical Gene Therapy Testing for Neurological Diseases
Watch this webinar to learn how JAX leverages validated models of neurodegenerative and neurodevelopmental disease to evaluate biodistribution, efficacy, and target engagement.
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JAX Humanized Mice PubCast: Acute Myeloid Leukemia + NSG-MHC I/II DKO Mice
In this episode, we delve into a publication that established a novel humanized mouse model of graft-versus-leukemia that better recapitulates the characteristics of AML relapse seen in patients.
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Emerging Models for Alzheimer's Disease
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Optimize Your Studies: Key Considerations with Mouse Neurological Models
During this webinar, we discuss best practices for model selection, study design, and experimental reproducibility.
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Selecting and Using Mouse Models in Neurodevelopmental Drug Discovery
Join the JAX In Vivo Services team as they share insights from extensive neurobiology drug discovery studies conducted for both academic and commercial clients.
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Upcoming Release of iPSC Lines
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JAX Tech Talk Episode 68: Let’s Talk iPSC Disease Models as a Tool in Drug Discovery (Nov. 7, 2023)
During this JAX Tech Talk, Dr. Steven Rodriguez, Lab Head of the Rare & Neurological Diseases Therapeutic Area at Sanofi, discusses how his group uses iPSC models to understand disease biology.
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The Complexity of Rare Disease
Learn about the complexity of rare disease and the unique difficulty it presents to patients and families by exploring the patient journey—from diagnosis to research to drug development.
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