SITC 2023 Comparison of Blinatumomab and Biosimilar CD19xCD3 BiTE responses in PBMC-Humanized Mice Used as a Preclinical Lymphoma Mouse Mode
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Oncology
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2023 AALAS P403 Comparing tumor erosion rate following P16MC38 subcutaneous (SC) vs. mammary fat pad (MFP) injections
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2023 AALAS P402 Evaluating sub-renal capsule cavity tumor growth in immunodeficient NSG-MHC I/II double knock-out mice
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Immunomodulatory Profile
Bispecifics and CAR-T sequences
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The Next Generation of Humanized Mice for Translational Research - Dr. Michael Brehm
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2023 AACR Mouse models of cancer available from The Jackson Laboratory
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In vivo Preclinical Efficacy & Safety of CAR-T, -NK, and -Myeloid Based Therapies
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JAX Tech Talk Episode 60: Let's talk JAXBoy, a new and improved CD45.1 C57BL/6 mouse (Nov. 8, 2022)
November 8, 2022 - Congenic markers are a key tool for tracking cells in adoptive transfer and competitive bone marrow transplant experiments. But did you know that traditional strains harbor an artif
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2022 SITC 1427 Comparative analysis of human immune subsets and Rituximab antitumor response across multiple NSG strains engrafted with huma
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2022 SITC 1258 PBMC humanized mouse model with clinical relevance in assessing the safety profile of 4-1BB agonists utomilumab and urelumab
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Preclinical Assessment of Engineered Immunoglobulins in Immune Humanized Mice
Presented by Brian Soper, Ph.D. - Senior Scientific Engagement Manager, The Jackson Laboratory
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The Application of Humanized Mouse Models to Study LILRB-Mediated Regulation of Myeloid Cells
Presented by Ali Roghanian, Ph.D., Lecturer (Assistant Professor) in Cancer Immunology & Immunotherapy, University of Southampton
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Patient management after genomic testing
Provides an overview of the option to receive medically actionable results unrelated to the presenting condition
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Modeling Human Melanoma To Understand And Treat Resistance To Immunotherapy
Meenard Herlyn, DVM, DSc discusses the development of a variety of 3D models, from human skin equivalents to organoids, mimicking cellular interactions in normal and malignant tissues.
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Cancer Susceptibility Genes
Lists genes that are associated with hereditary cancer and should be considered for referral when identified on a tumor test report.
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Testing to Identify Genomic Variants Related to Cancer
Defines and compares benefits and limitations of type of testing: somatic, paired somatic/germline and concurrent somatic + germline.
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Benefits of Exome Testing
Outlines advantages of exome testing across various clinical specialties
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Mapping Complex Traits in Mice
Learn about the study of complex traits genetics in mice. Find out how inbred mouse strains and advanced mouse populations enable complex traits genetics techniques, such as QTL mapping.
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How do I get from here to there? Navigating precision medicine in cancer
This scenario is more complicated than it may seem. With genomic tumor testing, a negative result is not always definitive. In some cases a genomic variant can be present but not detected by the...
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Modeling Chimeric Antigen Receptor (CARS) and T Cell Bispecific (TCB) Therapies in Mice
Modeling chimeric antigen receptor (CARS) and T cell bispecific (TCB) therapies in mice
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