Poster: Translational Humanized Models for Immunotherapy Drug Development | CHI 2024
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Conference Posters and Presentations
The Jackson Laboratory attends and hosts a number of conferences throughout the year. Below you will find a selection of posters our scientists have presented.
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Poster: Translational Humanized Models for Immunotherapy Drug Development | Immuno 2024
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Poster: Evaluating toxicity and efficacy of bispecific EGFRXCD3 T cell engager in solid tumor-bearing humanized animal model
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Poster: Assessing impacts of tumor burden and CAR-T cell dosage on the toxicity and efficacy profile of CD19 CAR-T therapy in a PBMC Model
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Poster: Modeling individual variability in CD19 CAR-T therapy - An in vivo study with PBMC-humanized mice
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Poster: The NSG-Flt3KO; Tg(hFLT3LG) hIL15 mouse strain improves engraftment of innate immune cells post-CD34+ humanization
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Poster: Establishing orthotopic renal cell carcinoma xenograft in PBMC-humanized immunodeficient NSG-MHC I:II double knock-out mice
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Poster: Hu-mouse model to assess PBMC donor derived autologous CD19 CAR-Ts for efficacy against Raji tumors and related Cytokine Release
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SITC 2023 Comparison of Blinatumomab and Biosimilar CD19xCD3 BiTE responses in PBMC-Humanized Mice Used as a Preclinical Lymphoma Mouse Mode
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SITC 2023 PBMC Humanized Mouse Model with Clinical Relevance in Assessing the Safety Profile of 4-1BB Agonist, Urelumab, in 5 Donors
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PEGS EU 2023 - A Novel, Translational Platform to Assess the Efficacy and Toxicity of Bispecific Antibodies
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PEGS EU 2023 - Predicting the Clinical PK of Candidate Therapeutic Antibodies
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PEGS EU 2023 - Translational Humanized Models for Immunotherapy Drug Development
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2023 AALAS P403 Comparing tumor erosion rate following P16MC38 subcutaneous (SC) vs. mammary fat pad (MFP) injections
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2023 AALAS P402 Evaluating sub-renal capsule cavity tumor growth in immunodeficient NSG-MHC I/II double knock-out mice
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2023 AACR The use of PBMC humanized mice to test the efficacy and safety of antibody and cell-based cancer immunotherapeutics
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2023 AACR Novel preclinical model for the evaluation of cytokine release syndrome in response to CD19xCD3 bispecific antibody in humanized m
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2023 AACR A new tumor-bearing humanized mouse model to evaluate the efficacy of bispecific T cell engager and monoclonal checkpoint antibodi
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2023 AACR Comparisons of Rituximab and CD19xCD3 BiTE antitumor response across multiple humanized NSG strains engrafted with human hematopoi
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2023 AACR Assessing individual variability in efficacy and toxicity of autologous and allogeneic chimeric antigen receptor T-cell immunother
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