Predictive Cancer Models Using Patient-Derived Xenograft Mice
Using patient-derived xenograft (PDX) mice enables modeling the heterogeneity of human cancer and conducting more translationally-relevant cancer research studies.
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JAX™ On-Demand Videos
This stream includes our JAX™ On-Demand Webinars
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Modeling Infectious Disease in the Mouse: Challenges and Innovations
Watch this video to learn how JAX inbred mouse strains can be used to model infection as well as treatment and prevention of human infectious diseases.
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Reproductive Biology of Mice
This video reviews mouse reproductive biology, focusing on optimizing the breeding productivity of research mouse colonies.
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Light Up Your Research: Use and Selection of Optogenetic Mouse Models
This video reviews the basics of optogenetic mouse models and how researchers are using them to investigate neural circuitries underlying complex behaviors and neural diseases.
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Making Sense of Mouse Nomenclature and Promoting Genetic Stability
What is in a name? From mouse strain nomenclature, you can determine genetic background, genetic modifications, who created the strain and who currently distributes it.
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Best Practices for Efficient Colony Management
In today's economic climate, research funding and vivarium space are becoming increasingly limited. As a result, investigators are challenged with managing their mouse colonies more efficiently.
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Aligning Health Surveillance and Risk in Embryo Transfer
Watch this video to learn about our new proactive approach for health monitoring of the embryo transfer method of mouse rederivation.
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Cre-lox Basics: Cre-lox Technology in Mouse Modeling
Cre-lox technology has quickly become one of the most widely used and versatile tools for genetically engineering mice for human disease modeling.
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Protect Your Research: Know Your B6 Mouse
The C57BL/6 inbred mouse (B6) is the most commonly used research strain. This strain is the most well characterized and the first to have its’ entire genome sequenced.
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Tips & Tricks for Care of NSG Mice
The revolutionary NOD scid gamma (NSG™) mouse model is used by investigators worldwide to advance research in cancer, infectious diseases and a wide array of immunological disorders.
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Tips for Working with Diabetic Mice
Genetic alterations predispose mice to develop human-like diabetes phenotypes. However, overlooking the environmental factors that influence those phenotypes can confound research results.
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Mouse Models for Cardiovascular Disease
Cardiovascular disease is the leading cause of morbidity and mortality worldwide. Our mouse model repository maintains hundreds of mouse models to accelerate research in coronary heart disease.
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CRISPR/Cas9 Explained
Did you know that CRISPR engineering can sometimes yield more than the allele you originally intended? Learn more about mosaicism, how to resolve it, and other CRISPR basics in this video.
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Research Using Aged B6 Mice: Considerations, Applications, and Best Practices
Aging studies are lengthy, resource intensive, and require advance planning. Learn special considerations for maximizing the translational value of data collected from aged research mice.
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Onco-Hu Mice for Evaluation of Immuno-Oncology Therapeutics
Watch this video to learn about cutting edge preclinical mouse platforms used to evaluate immuno-modulatory therapies for human cancer.
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Achieving Reproducible Mouse Studies
Success in the drug development pipeline depends on success in basic and preclinical research. Watch this video to learn about unique experimental design considerations for mouse-based research.
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Generating Mouse Models Using CRISPR/Cas9 Technology
Do you need to generate new mouse models within 3-4 months instead of 1-1.5 years? Revolutionary CRISPR/Cas technology enables rapid, economical model generation through precise genome editing.
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Onco-Hu Mouse Models for Cancer Immunotherapy Research Explained
Onco-Hu® models are a robust immuno-oncology platform for efficacy testing of novel immunotherapies targeting T cells and myeloid cells.
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Designing & Optimizing Mouse Breeding Schemes
Have you ever had to delay an experiment because you didn’t design your breeding scheme to produce enough knockout (KO) or control mice? Are you unsure of the most efficient way to set up your cross?
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Caring for Immunodeficient Mice: From Nude to NSG™
The revolutionary NOD scid gamma (NSG™) mouse model is used by investigators worldwide to advance research in cancer, infectious diseases and a wide array of immunological disorders.
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