Onco-Hu® Mouse Models
This video explores Onco-Hu® models, a robust immuno-oncology platform for efficacy testing of novel immunotherapies targeting T cells and myeloid cells. The platform is based on NSG™ and NSG™-SGM3 tr
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JAX™ On-Demand Videos
This stream includes our JAX™ On-Demand Webinars
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Mouse Models of Coronavirus Infection
In this webinar, we discuss upcoming and established strains in the JAX COVID-19 Model Portfolio, in the context of in vivo findings with SARS-CoV2 and related viruses.
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Predictive Pre Clinical Oncology Studies Using Patient-Derived Xenograft Platforms
This on-demand webinar provides strategies for using PDX models in predictive preclinical research and an introduction to PDX models for immuno-oncology research.
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In Vivo Preclinical Efficacy & Safety of CAR-T, -NK, and -Myeloid Based Therapies
Technical Information Services Manager, Brian Soper, Ph.D., explores recent advances in CAR mediated strategies for human immuno-oncology. Recorded on 4-7-22
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Designing Your In Vivo Studies
September 9, 2021 - Learn about unique experimental design considerations and critically important topics that affect the reproducibility of your In Vivo research studies.
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Introduction to In Vivo Platforms for Cancer Immunotherapy
(recording date: 3/04/2021) Grace Berryhill, Ph.D. provides an overview of in vivo platforms being used to improve the translational relevance of cancer immunotherapies. Covered in this webinar are:
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Human Immune System Engrafted Platforms for More Translatable Preclinical Research
Senior Manager and Technical Information Scientist, Brian Soper, Ph.D., discusses human immune system engrafted platforms and preclinical research.
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Study Considerations and Preclinical Testing to Study Aging
Dr. Kaitlyn Gilland, Senior Technical Information Scientist, discusses working with aged C57BL/6J mice, study considerations, and preclinical testing.
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Efficacy and Safety of Therapeutics in Immuno-modulatory Induced Cytokine Release Syndrome
Brian W. Soper, Ph.D. speaks about the efficacy and safety of therapeutics in immuno-modulatory induced cytokine release syndrome. Dr. Soper discusses human PBMC engraftment profiles; modeling human c
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Overcoming the Challenges of Working With Diabetic Mice
In this seminar, we discuss the environmental factors that can influence diabetic phenotypes and can confound research results.
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Efficient Mouse Colony Management
Would you like to minimize the resources you use to support your research mouse colonies? During this seminar, we discuss strategies to save cost and time by efficiently managing mouse colonies.
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Guidelines for Sizing Experimental Mouse Colonies
Learn about estimating the optimal number of breeder mice required to support your ongoing research and to include within budgets for grant applications or in Animal Care and Use Protocols.
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Improving Translational Relevance with Humanized NSG™ Mice
Watch this video to learn the process of generating and characterizing “humanized” NSG™ (Hu-NSG™) mice and view data demonstrating preclinical research applications of these novel mouse models.
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Generating Better Mouse Models for Your Research: Approaches and Considerations
Check out this video for experience-based insights that can help you make decisions during your model development process.
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Genetic Drift – What It Is and How to Minimize Its Impact on Your Research
Watch this video to learn how The Jackson Laboratory's unique Genetic Stability Program effectively limits cumulative genetic drift.
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Designing & Optimizing Mouse Breeding Schemes
Watch this video to get a refresher on the fundamentals of basic mouse genetics and learn some tricks from our experts to plan your next experiment better.
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Beyond the Knockout: Using Cre-lox Technology to Model Cancer, Neurodegenerative Diseases and More
Learn how Cre-lox technology is being used to model various human cancers and how it is furthering our understanding of neurodegenerative disorders such as ALS and Parkinson's disease.
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CRISPR/Cas9 - Moving from Founder Mice to Phenotyping
Watch this video to learn the complexities associated with alleles that can be generated, how to deal with mosaicism, and how to move from founder mice to larger cohorts for phenotype characterization
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Modeling Infectious Disease in the Mouse: Challenges and Innovations
Watch this video to learn how JAX inbred mouse strains can be used to model infection as well as treatment and prevention of human infectious diseases.
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Reproductive Biology of Mice
This video reviews mouse reproductive biology, focusing on optimizing the breeding productivity of research mouse colonies.
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