What Do Experimental Mice Really Cost?
In this presentation, we share a data-supported framework designed to trim costs, save time, and reduce the number of animals used for colony maintenance and cohort production.
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This stream includes our JAX™ On-Demand Webinars
In this presentation, we share a data-supported framework designed to trim costs, save time, and reduce the number of animals used for colony maintenance and cohort production.
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February 20, 2024 - During this presentation, we compare strategies for immune humanization of NSG variants to support translatable preclinical immunology and oncology research.
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In this webinar, we discuss cre-lox technology, a widely used and sophisticated tool to create general knockouts, conditional knockouts, and reporter strains.
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During this seminar, we discuss unique experimental design considerations for mouse-based research.
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January 16, 2024 - In this webinar, we discuss the most widely used immunodeficient mouse models and essential considerations for selecting the most appropriate model.
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Omitting sex as a biological variable has several consequences. Watch this webinar to learn the scientific impact sex bias has on your research.
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During this webinar, we discuss preclinical data showcasing efficacy and safety testing of immunotherapies in immune humanized mouse models.
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During this webinar, we discuss how mouse phenotypes change over time, review study design considerations, and share several examples of using aged C57BL/6J mice in preclinical studies.
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In this webinar, we discuss the humanized FcRn platform, an effective tool that provides relevant PK data for candidate therapeutic antibodies and albumin-conjugated molecules.
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In this webinar, we will introduce two new enhanced NSG models developed at The Jackson Laboratory: NSG-SGM3-IL15 and NSG-FLT3.
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Learn about Hu-PBMC NSG models that can be used to test the efficacy of human T cell immunomodulatory therapeutics for graft-versus-host disease (GvHD), autoimmune disorders, and cancer.
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Watch this webinar to learn about the strengths and weaknesses of popular mouse models of human type 2 diabetes and obesity. webinar to learn about: • The benefits and limitations of some common
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In this webinar, we cover the considerations for choosing and using the most appropriate B6 substrain for your research needs.
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Learn about finding and selecting mouse models, the basics of mouse nomenclature, the importance of choosing the appropriate controls for your experiment, and how genetic drift affects your colony.
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Watch this webinar to learn about Experimental Autoimmune Encephalomyelitis (EAE), which serves as the gold standard preclinical model for MS research.
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Watch this webinar to learn ways to support research excellence while balancing the principles of the 3Rs (Replacement, Reduction, and Refinement), a framework for humane in vivo research.
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Learn how to overcome the challenges to develop gene therapies, specifically for neurodevelopmental and neurodegenerative diseases.
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Watch this webinar to review phenotypic characteristics, considerations for selecting therapeutically relevant ALS models, and more!
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This video explores Onco-Hu® models, a robust immuno-oncology platform for efficacy testing of novel immunotherapies targeting T cells and myeloid cells. The platform is based on NSG™ and NSG™-SGM3 tr
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In this webinar, we discuss upcoming and established strains in the JAX COVID-19 Model Portfolio, in the context of in vivo findings with SARS-CoV2 and related viruses.
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