How-to Guide for Selecting Xenografts & Mouse Models for Preclinical Cancer Research
If you’re gearing up to evaluate your drug candidates in clinically translatable, in vivo models, this webinar is for you.
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JAX™ On-Demand Videos
This stream includes our JAX™ On-Demand Webinars
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What Do Experimental Mice Really Cost?
In this presentation, we share a data-supported framework designed to trim costs, save time, and reduce the number of animals used for colony maintenance and cohort production.
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Comparing Immune-Humanized Mouse Platforms for Preclinical Applications
February 20, 2024 - During this presentation, we compare strategies for immune humanization of NSG variants to support translatable preclinical immunology and oncology research.
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Using Cre-lox Technology in Mouse Modeling
In this webinar, we discuss cre-lox technology, a widely used and sophisticated tool to create general knockouts, conditional knockouts, and reporter strains.
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Designing Reproducible Preclinical Research Studies
During this seminar, we discuss unique experimental design considerations for mouse-based research.
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Comparing Immunodeficient Models for Cancer, Immunity, and Transplant Research
January 16, 2024 - In this webinar, we discuss the most widely used immunodeficient mouse models and essential considerations for selecting the most appropriate model.
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The Consequences of Sex Bias in Preclinical Research
Omitting sex as a biological variable has several consequences. Watch this webinar to learn the scientific impact sex bias has on your research.
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Translatable Efficacy & Safety Testing of mAb, Bispecific, & CAR T Therapies
During this webinar, we discuss preclinical data showcasing efficacy and safety testing of immunotherapies in immune humanized mouse models.
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Key Considerations to Optimize Preclinical Aging Studies
During this webinar, we discuss how mouse phenotypes change over time, review study design considerations, and share several examples of using aged C57BL/6J mice in preclinical studies.
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De-Risk Therapeutic Antibody Drug Development Using Humanized FcRn Platforms (Oct. 24, 2023)
In this webinar, we discuss the humanized FcRn platform, an effective tool that provides relevant PK data for candidate therapeutic antibodies and albumin-conjugated molecules.
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New Immune-humanized Models Support More Diverse Human Immune Cell Lineages
In this webinar, we will introduce two new enhanced NSG models developed at The Jackson Laboratory: NSG-SGM3-IL15 and NSG-FLT3.
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Rapid In Vivo Evaluation of Immuno-Modulatory Therapies Using Hu-PBMC NSG™ Mice
Learn about Hu-PBMC NSG models that can be used to test the efficacy of human T cell immunomodulatory therapeutics for graft-versus-host disease (GvHD), autoimmune disorders, and cancer.
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Comparing Mouse Models for Obesity and Diabetes Research
Watch this webinar to learn about the strengths and weaknesses of popular mouse models of human type 2 diabetes and obesity. webinar to learn about: • The benefits and limitations of some common
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The Many Faces of C57BL/6 Mice: Research Impact of B6 Substrain Differences
In this webinar, we cover the considerations for choosing and using the most appropriate B6 substrain for your research needs.
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Essential Tips for Choosing and Using Mouse Models in Research
Learn about finding and selecting mouse models, the basics of mouse nomenclature, the importance of choosing the appropriate controls for your experiment, and how genetic drift affects your colony.
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In Vivo Platforms for Autoimmune Pharmacology: MS-EAE Capabilities
Watch this webinar to learn about Experimental Autoimmune Encephalomyelitis (EAE), which serves as the gold standard preclinical model for MS research.
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Support the 3 R’s with Effective Mouse Colony Management Practices
Watch this webinar to learn ways to support research excellence while balancing the principles of the 3Rs (Replacement, Reduction, and Refinement), a framework for humane in vivo research.
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Preclinical Assessment of Investigational Gene Therapy Products for Neuroscience
Learn how to overcome the challenges to develop gene therapies, specifically for neurodevelopmental and neurodegenerative diseases.
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In Vivo Drug Discovery Platforms for Amyotrophic Lateral Sclerosis
Watch this webinar to review phenotypic characteristics, considerations for selecting therapeutically relevant ALS models, and more!
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Onco-Hu® Mouse Models
This video explores Onco-Hu® models, a robust immuno-oncology platform for efficacy testing of novel immunotherapies targeting T cells and myeloid cells. The platform is based on NSG™ and NSG™-SGM3 tr
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