Immune Humanized Mice

Advancing Immunotherapy Research with PBMC-Engrafted NSG* Models

Peripheral blood mononuclear cell (PBMC)-engrafted NSG mice serve as a robust model for studying T cell activation, immune modulation, and therapeutic intervention.

JAX Presentation - Use of Humanized Mouse Models in Drug Development - Brian Soper, Ph.D.

Translatable Efficacy & Safety Testing of mAb, Bispecific, & CAR T Therapies

During this webinar, we discuss preclinical data showcasing efficacy and safety testing of immunotherapies in immune humanized mouse models.

New Immune-humanized Models Support More Diverse Human Immune Cell Lineages

In this webinar, we will introduce two new enhanced NSG models developed at The Jackson Laboratory: NSG-SGM3-IL15 and NSG-FLT3.

Humanized Mice: Activity of Cytotoxic and Immunomodulatory IgG Antibodies

Anja Lux, PhD, Friedrich Alexander University, speaking at The Jackson Laboratory EU Symposium. A humanized mouse model to study activity of cytotoxic and immunomodulatory human IgG antibodies.

Humanized Mice: Application of Humanized Mice in Manipulation of Myeloid Cells

Ali Roghanian, PhD, University of Southampton speaking at The Jackson Laboratory EU Symposium. The application of humanized mice in manipulation of myeloid cells.