Intro Why do millions of Americans and others around the world participate in consumer genomics? For many, testing provides a window into their innermost self, their genome, and a new way to...
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We invite you to explore our comprehensive portfolio of COVID-19 models.
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For the first time ever, drug developers have the option to accurately assess immunotoxicity and drug efficacy in the same study utilizing a novel humanized platform.
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Happy Black and African American History Month from The Jackson Laboratory! According to The History Channel, Black History Month (also known as African American History Month) is an annual...
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Assessing novel therapeutics that function to modulate the interaction between the human immune system and cancer cells requires advanced preclinical efficacy testing platforms. Immunologically...
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Genomic testing in healthcare is here to stay. Use of testing is increasing, not only in the traditional sense (think hereditary cancer or prenatal genetics), but also outside the doctor’s...
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Intro We’ve all felt this, to the point where I hesitate to say it out of fear of sounding trite. But, 2020 has been a year like no other we’ve known in recent memory; tumultuous in so many ways....
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Abstract When time isn’t on anyone’s side, how can clinicians and patients make the most educated decision for their treatment? Implementation of next-generation sequencing to uncover the...
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The Clinical & Continuing Education team at The Jackson Laboratory is excited to announce a new Diversity, Equity & Inclusion series within our blog communications with healthcare providers. We...
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Daniel Cortés-Perez Daniel Cortés-Perez Postdoctoral associate Daniel Cortés-Perez, Ph.D., conducts research in...
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Maria is a 70-year old woman in your practice with a new diagnosis of advanced non-small cell lung cancer (NSCLC). You plan to test a biopsy specimen for a handful of recommended genes, but what...
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Malik is your 6-year-old patient with autism and global developmental delay. DNA testing did not identify a pathogenic variant (mutation) using a multi-gene neurology panel. However, a variant of...
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Most traditional laboratory mouse strains were established by taking a mouse with unique characteristics and inbreeding it to produce a mouse population that is composed of virtually identical...
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The term “humanized” mouse can mean many things to many people, but we’ll define it as a mouse that harbors engrafted human tissue or cells, such as immune cells. Here are some helpful tips.
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You may have noticed that the latest biomedical breakthroughs are utilizing more and more humanized mice. But, what is a humanized mouse and why would scientists want to utilize this type of...
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Under certain circumstances in patients, the human immune system can spin out of control and become highly toxic, resulting in cytokine release syndrome (CRS). CRS has been observed in certain...
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When people think of innovation, often times they think of new products like iPhones and companies like SpaceX. But innovation spans far beyond what one may typically think of and can be applied...
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Beta-amyloid peptid. The amyloid precursor protein being cleaved by gamma and beta secretases and releasing the amyloid beta peptide, which can accumulate to amyloid plaques, one of the main...
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How to address secondary findings from genomic testing Consider this scenario: Jayne is 50 years old and has experienced progressing neurological symptoms over the past two years with no...
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Immunodeficient mice are invaluable tools for immunology, infectious disease, oncology, hematopoietic, and regenerative medicine studies. They can serve as hosts for engraftment of mouse tumor...
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