Learn about new technologies and discoveries focused on precise and personalized treatments for patients.
In the field of stem cell research, the quest to define a “reference” induced pluripotent stem cell (iPSC) line is ongoing and nuanced. As we deepen our understanding of human biology, one thing...
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Cre-lox and other recombinase systems are among some of the most versatile and impactful genetic tools in recent decades. These tools enable precise control over the timing and localization of...
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Induced pluripotent stem cells (iPSCs) have become indispensable tools in modern biomedical research and are transforming how we model human disease, discover drugs, and explore regenerative...
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The Reproducibility Crisis in Preclinical SciencePreclinical research, the foundation of biomedical innovation, is facing a reproducibility crisis. A growing number of studies fail to replicate...
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Digital monitoring technology is revolutionizing biomedical research. While wearable devices have already proven invaluable for early disease detection and progression monitoring in clinical...
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What is a humanized mouse model? A seemingly straightforward question, with the most common answer – it depends. The term “humanized” can mean several things and depends on the context.In the...
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The Growing Potential of Antibody-Based TherapeuticsAntibodies have been part of the therapeutic toolbox for over 40 years and represent an exciting drug modality to treat various diseases, in...
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(Bar Harbor, Maine, and Allentown, N.J. – Nov. 3, 2024) – The Jackson Laboratory (JAX), a nonprofit biomedical research institution and a global leader in mouse models of human disease, has joined...
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The Jackson Laboratory has developed a computer vision-based method to accurately and continuously measure mouse body mass.
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We review strategies and mouse models used to develop highly promising therapeutic treatments using the body’s own immune system in the fight against cancer.
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Limitations to scientific progress often arise not from a lack of curiosity or imagination, but rather from the tools and technologies available. While some research questions can be sufficiently...
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We recently published a paper in Journal of Genetic Counseling outlining our successful team-based approach to developing education for cardiology clinicians. Our collaboration with clinical and...
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I started covering the field of human genomics in depth around 2008. It was a time when whole genome sequencing (WGS) still cost millions of dollars per genome, and genome editing methods were so...
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How do you decide which mouse model is most applicable for your research question or to test your therapeutic? With over 13,000 available mouse models at the Jackson Laboratory, it can be...
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Genetic counselors at The Jackson Laboratory (JAX) impact research and clinical education, developing and implementing initiatives that improve clinical care. Below are the top five ways JAX...
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Through this unique training opportunity, students apply for admission into doctoral programs at one of our partner institutions, and follow their academic degree requirements, while performing...
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In this episode of Stoveside Chats, Moses Davis, director for diversity, equity and inclusion at JAX, joins colleague Mai Hendrix for an engaging conversation about their personal experiences with...
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Genetics on Capitol Hill The Jackson Laboratory had the unique opportunity to travel to Capitol Hill for the Congressional Life Sciences Fair on July 19, 2023. Hosted by the Coalition for Life...
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Humanized mice, defined as animals carrying human genes or cells, are relative newcomers to the drug development field. While regulatory agencies routinely accept IND filings with data generated...
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“Doing more of what we have today is not enough,” said National Cancer Institute Director Monica Bertagnolli, M.D., at the AACR annual meeting, “We need much more to cover the last mile.” What is...
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