Mapping Complex Traits in Mice

This MiniCourse is self-paced and takes 1 to 2 hours to complete. At the end of the MiniCourse, you will be able to define how inbred mouse strains and advanced mouse populations are used in complex traits genetics techniques, such as Quantitative Trait Locus (QTL) mapping. You have the option to purchase a JAX digital badge credential and certificate. In order to purchase and display a JAX digital badge credential and certificate for this MiniCourse, you must complete the Core Lessons and take the Self-Review Quiz (scoring at least 70%).

• Basics of QTL mapping
• QTL analysis example 
• Phenotype distribution of a QTL study
• Genetic reference populations for genetic mapping
• High diversity mouse populations for genetic mapping
• Estimating genetic effects
• Logarithm of the odds (LOD) support intervals 
• Effect of covariates in QTL statistical modeling

This MiniCourse is designed to meet the needs of people who are new to utilizing laboratory mice for complex traits genetic and genomic research projects, including graduate and postdoctoral students, research assistants, early career scientists, lab technicians, and advanced undergraduates with a background in biology.

As an independent, nonprofit biomedical research institution founded in 1929, The Jackson Laboratory leverages its unique combination of research, education and resources to achieve its mission: to discover precise genomic solutions for disease and empower the global biomedical community in its shared quest to improve human health. We offer comprehensive educational programs for scientists throughout their careers, from high school students and teachers to researchers at all experience levels, and for clinical providers interested in incorporating genetics and genomics into their practices.

While we are not an accredited higher education institution, we offer a variety of education programs — including free non-credit bearing MicroLessons and MiniCourses, with optional digital badge credential and certificate for purchase — designed to educate current and future scientists and to provide critical resources, data, tools and services to researchers worldwide.

MiniCourse topics address both foundational content and the research areas in which The Jackson Laboratory has earned a reputation for scientific leadership and excellence.

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If you need technical support, please email: Online and Digital Education at The Jackson Laboratory.