JAX is here to get you from model selection to IND-enabling data in our shared quest to develop cures for neurological disorders and rare and orphan diseases.
Watch this webinar to learn how JAX leverages validated models of neurodegenerative and neurodevelopmental disease to evaluate biodistribution, efficacy, and target engagement.
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During this webinar, we discuss best practices for model selection, study design, and experimental reproducibility.
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Join the JAX In Vivo Services team as they share insights from extensive neurobiology drug discovery studies conducted for both academic and commercial clients.
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Learn how to overcome the challenges to develop gene therapies, specifically for neurodevelopmental and neurodegenerative diseases.
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The Jackson Laboratory is the exclusive service provider for robust, reliable, reproducible gene therapy, efficacy, and safety studies in the C9orf72 mouse model, the most common form of familial ALS.
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Dr. Mark Cookson talks about the unique aspects of the collection of human isogenic iPSC lines and how it can benefit the wider scientific community in their shared quest to understand and fight ADRD.
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Watch this webinar to review phenotypic characteristics, considerations for selecting therapeutically relevant ALS models, and more!
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The term humanization is used, to much confusion, to mean several different things in mouse research. While broad in scope and technique, all humanized mouse models share a common goal – to better lev
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Aug. 10, 2021 - In this episode, we will explore the use of Cre-lox technology to control gene expression in neuronal cell types, and more.
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The establishment of a new platform to assess preclinical allele dependent phenotypes
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October 27, 2020 - In this episode, we share with you highlights of JAX preclinical research studies using mouse models for ALS, Rett Syndrome, Friedreich's Ataxia, and more!
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Join Cat Lutz, Ph.D., Senior Director In Vivo Pharmacology & Mouse Repository at JAX as she'll discuss neurodegenerative diseases, rare diseases, and her group’s latest work in preclinical studies usi
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Beta-amyloid peptid. The amyloid precursor protein being cleaved by gamma and beta secretases and releasing the amyloid beta peptide, which can accumulate to amyloid plaques, one of the main...
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