Human HSC & PBMC Platforms for In Vivo Immune Modulatory Drug Discovery
Watch this webinar to learn more about JAX's advanced humanized platforms that support in vivo human immune cell development and function.
Watch Video
JAX humanized NSG mice represent an innovative and cost-effective platform to stimulate trials, evaluate multiple drugs alone or in combination, and produce reliable predicative data. Explore our collection of humanized mice resources and learn how this innovative platform models immunity to study and evaluate treatments for a variety of human diseases.
Watch this webinar to learn more about JAX's advanced humanized platforms that support in vivo human immune cell development and function.
Watch Video
Peripheral blood mononuclear cell (PBMC)-engrafted NSG mice serve as a robust model for studying T cell activation, immune modulation, and therapeutic intervention.
Watch Video
Presented by Jan Terje Andersen, Ph.D., Professor in Biomedical Innovation, University of Oslo
Watch Video
Presented by Martin Lechmann Ph.D., DMPK/PD Project Lead (DPL) Biologics, Roche Diagnostics GmbH
Watch Video
Presented by Michael Kiffe, Ph.D., Director PK Sciences / Translational Medicine, & Monika Gajewska, Ph.D., M&S Group, PK Sciences, Novartis Pharma AG
Watch Video
This webinar explores how to leverage humanized mouse models to expedite preclinical research in biologic therapeutics.by providing a rigorous scientific framework and practical insights for l
Watch Video
Learn about JAX's enhanced innate immune models: the CD34+ engrafted NSG-FLT3 and NSG-FLT3-IL15 mice, presented by Michael Brehm, Ph.D., UMass Medical School.
Watch Video
During this webinar, we will discuss the most widely used immunodeficient mouse models and important considerations for selecting the most appropriate model.
Watch Video
In this episode, we delve into a publication that established a novel humanized mouse model of graft-versus-leukemia that better recapitulates the characteristics of AML relapse seen in patients.
Watch Video
Watch Video
Watch Video
Watch Video
Watch Video
Read Flipbook
During this presentation, we will compare strategies for immune humanization of NSG variants to support translatable preclinical immunology, and oncology research. researchers a powerful tool for cha
Watch Video
In this presentation, we introduce The Jackson Laboratory’s most comprehensive immune humanized mouse platform to date: NSG- FLT3-IL15.
Watch Video
Learn about an immune humanized model of irritable bowel disease (IBD) used to investigate the mechanism of action and evaluate the therapeutic efficacy of interleukin-2 in treating ulcerative colitis
Watch Video
JAX Study Director Aaron Rose, Ph.D., explores how biological therapeutics are reshaping the drug development process and why humanized models are essential for advancing biologics programs.
Watch Video
In this PubCast, we delve into Roche’s integration of humanized mice in their preclinical drug development pipeline to assess the safety and efficacy of their CD19-CD28 bispecific.
Watch Video
Join us as we discuss a collaborative effort between academia and a biopharmaceutical company, which utilized humanized mice to explore the role of mast cells in the melanoma tumor microenvironment.
Watch Video
Loading More...