Self-paced JAX Online MiniCourse
Basics of CRISPR/Cas9
Get your research started with CRISPR/Cas9 genetic engineering technology by learning about nuclease biology, somatic and germline gene editing, avoiding off-target events and more.
This MiniCourse is self-paced and takes 1 to 2 hours to complete. At the end of the MiniCourse, you will have gained a basic understanding of utilizing the CRISPR/Cas9 gene editing technology in order to manipulate a gene of interest. You have the option to purchase a JAX digital badge credential and certificate. In order to purchase and display a JAX digital badge credential and certificate for this MiniCourse, you must complete the Core Lessons and take the Self-Review Quiz (scoring at least 70%).
- Brief historical outline of targeted nucleases that lead to DNA cuts
- Somatic cell and germline gene editing
- Basic mechanism of CRISPR/Cas9 genome engineering technology
- Dead Cas9 protein
- CRISPR/Cas9 strategies to create a better mouse model
- CRISPR/Cas9 complications, including off-target events and founder mosaicism
- Practical applications in the clinic
This MiniCourse is designed to meet the needs of people who utilize JAX laboratory mice for genetic and genomic research projects, including: scientists, research assistants, lab technicians, graduate and postdoctoral students, mouse colony managers and staff.
As an independent, nonprofit biomedical research institution founded in 1929, The Jackson Laboratory leverages its unique combination of research, education and resources to achieve its mission: to discover precise genomic solutions for disease and empower the global biomedical community in its shared quest to improve human health. We offer comprehensive educational programs for scientists throughout their careers, from high school students and teachers to researchers at all experience levels, and for clinical providers interested in incorporating genetics and genomics into their practices.
While we are not an accredited higher education institution, we offer a variety of education programs — including free non-credit bearing MicroLessons and MiniCourses, with optional digital badge credential and certificate for purchase — designed to educate current and future scientists and to provide critical resources, data, tools and services to researchers worldwide.
MiniCourse topics address both foundational content and the research areas in which The Jackson Laboratory has earned a reputation for scientific leadership and excellence.
- Audio speakers or headphones
- Screen resolution of 800X600 or higher
- Adobe Reader 5.0 or higher
- 1GB of RAM
- 2GHz processor
It is always recommended to use the most up-to-date browsers and high-speed internet connections for optimal system performance.
If you need technical support, please email: Online and Digital Education at The Jackson Laboratory.