Effects of Aging on Immunosenescence and Checkpoint Inhibitor Efficacy in a C57BL/6J Syngeneic Model

August 25, 2020

Presented at the JAX Immunology Scientific Sessions, Dr. Jiwon Yang of The Jackson Laboratory outlines her recent work in establishing a mouse model that exhibits immunosenescence and studying how immunosenescence affects checkpoint inhibitor efficacy in a C57BL/6J syngeneic model.

Effects of Aging on Immunosenescence and Checkpoint Inhibitor Efficacy in a C57BL/6J Syngeneic Model

Preclinical Evaluation of Efficacy and Cytokine Release of Bispecific T Cell Engagers in Hu-NSG Mice

An In Vivo Model to Evaluate Donor-Dependent Cytokine Release