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Highly Advanced Immune Humanized Platforms for Immuno-Oncology Drug Discovery

Highly Advanced Immune Humanized Platforms for Immuno-Oncology Drug Discovery

Published Date July 30, 2026

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Home Sweet Home: Leveraging Continuous Home-Cage Monitoring to Improve Science and Animal Welfare

Learn how the Behavioral Phenotyping Core at Seattle Children’s Research Institute expanded its capabilities with the integration of the Allentown Discovery IVC Rack powered by The Jackson Laboratory.
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Partner with JAX-NYSCF

Learn more about the JAX-NYSCF partnership to accelerate cures for the major diseases of our time through stem cell research, from large iPSC cohorts for specific disease areas to developing...

Other content in this Stream

15 days ago
Mouse Models that Bridge the Gap in Immunotherapy Discovery

Immunotherapy is an effective way to fight cancer using the body’s own immune system. From basic research to drug discovery, in vivo modeling has become the cornerstone of immunotherapy...

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18 days ago
What is a Humanized Mouse? FAQs about models for immunology, immuno-oncology, and pharmacokinetics.

What is a humanized mouse model?A humanized mouse refers to a mouse that carries some aspect(s) of human biology. For instance, “humanized” could refer to a mouse expressing a human gene...

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9 days ago
Mouse Models Shaping Antiviral Vaccine Development

This webinar explores how diverse mouse models have been used to develop and refine antiviral vaccines.

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10 days ago
Optimizing Experimental Design Using Aged Mouse Models

This webinar addresses critical elements of experimental design that support the efficiency, rigor, and reproducibility of aging studies.

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10 days ago
Understanding the C57BL/6J Mouse Model: From Genetic Origins to Research Applications

This webinar highlights many aspects of the C57BL/6J strain, one of the most widely utilized inbred models in biomedical research.

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about 2 months ago
ABCs of Antibody Discovery: Leveraging Biological Foundations and Modern Platforms

This webinar discusses the shift toward antibody therapeutics as a more precise and targeted alternative to traditional therapies.

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about 1 month ago
Envision 5.0 - A Platform Built for Home Cage Research

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about 1 month ago
Diet-induced Obese Tg32 (hFcRN) : a New Platform for PK Analysis of Anti-obesity Peptide-Fc Based and Antibody Therapeutics

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2 months ago
Advancing Translational Relevance in Preclinical Mouse Models for Alzheimer’s Disease

Watch this webinar for guidance on the informed selection of in vivo mouse models for the preclinical evaluation of therapeutic candidates for Alzheimer’s disease.

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11 days ago
An Introduction to iPSCs: Applications, Models, and Best Practices

In this webinar, we’ll cover the basics of iPSCs, showcase real-world research applications, and discuss the biological questions these models help answer.

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3 months ago
An Advanced PBMC-Humanized NSG-S15-DKO Mouse Model for Comprehensive Evaluation of Immunotherapeutics

What You'll Learn:PBMC models enable in vivo human immune system studiesDelayed GvHD supports longer, more flexible study windowsNSG-S15-DKO shows:Enhanced multi-lineage engraftment (T, NK,...

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10 days ago
S15-DKO: New Platform for Engraftment of Human PBMC Supporting Multilineage Immune Cells, Low GvHD

Learn about the S15‑DKO strain (NSG-NSG‑MHC I/II DKO × NSG‑SGM3‑IL15), which supports broader human immune cell engraftment (T, B/plasma, NK, cDC, macrophages, γδ T cells) without acute xGvHD.

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about 1 month ago
The JAX-NYSCF Global Stem Cell Array®️

Automated platform to generate high-quality induced iPSC lines and differentiate them into diverse, disease-relevant cell types. Advanced capabilities for efficient, reproducible research.

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10 days ago
Home Sweet Home: Leveraging Continuous Home-Cage Monitoring to Improve Science and Animal Welfare

Learn how the Behavioral Phenotyping Core at Seattle Children’s Research Institute expanded its capabilities with the integration of the Allentown Discovery IVC Rack powered by The Jackson Laboratory.

Watch Video
about 1 month ago
Partner with JAX-NYSCF

Learn more about the JAX-NYSCF partnership to accelerate cures for the major diseases of our time through stem cell research, from large iPSC cohorts for specific disease areas to developing...

Read More
3 months ago
New JAX NSG portfolio strains support development of human NK cells in oncology models

IntroductionNatural killer (NK) cells occupy an intriguing niche between adaptive and innate immunity. Like cytotoxic T lymphocytes, they can recognize and kill infected or malignant cells and...

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about 1 month ago
Powering Discovery with JAX iPSC Models

View highlights and comparison of JAX genetically engineered isogenic iPSC and donor-derived, disease-specific iPSC lines.

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3 months ago
Comparing Mouse Models for Metabolic Disease: Diabetes, Obesity, and MASH

Watch this webinar to learn how different mouse models capture different facets of human metabolic disease.

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4 months ago
Cre Lox Breeding for Beginners, Part 1

Simply put, the Cre/lox system rocks. It is one of the most powerful tools in the mouse geneticist’s toolbox. Why? Well, it enables them to generate tissue-specific and inducible knockouts and...

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4 months ago
Cre Lox Breeding for Beginners, Part 2

In a previous post I discussed breeding Cre/lox mice to generate tissue-specific and inducible conditional knockout mouse strains. I would now like to continue the discussion of breeding Cre/lox...

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