They're More than Mice They're J Mice
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Manuals and Guides
Explore a wealth of knowledge on diverse topics through our Manuals and Guides. From laboratory animal care to cutting-edge research methodologies, our curated collection offers valuable insights for professionals across various fields. Elevate your knowledge and stay informed with JAX.
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Quick Guide to Mouse Nomenclature
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Diversity Mice User Guide
This user guide is designed to introduce you to the core concepts of genetic diversity, present diversity models, and their key features.
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Aged C57BL/6J Mice: Research Applications & Colony Management Considerations
Join JAX's Rick Huntress as he discusses the latest research from Any Schile, Ph.D. on aged mice and colony management. They'll talk about some advantages of utilizing aged mice, how experiments diffe
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Generating Better Mouse Models for Your Research: Approaches and Considerations
Check out this video for experience-based insights that can help you make decisions during your model development process.
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JAX Resources for the Management of Transgenic Mice
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JAX Consulting Advisory Services
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Evidence-Based Selection of the Starting Dose in First-in-Human Clinical Trials Using Humanized Mouse Models
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In Vivo Evaluation of Bispecific T-Cell Engager Efficacy and Safety
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Achieving Relevant Preclinical Characterization of CAR T Cell Therapies
This whitepaper examines the constraints and challenges inherent in each CAR T study type and how to overcome them with in vivo studies using fully humanized mouse models.
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A MHC Class I & II Deficient Platform Humanized with PBMCs
JAX NSG-MHC I/II KO mice readily engraft tumors and human PBMCs, have delayed GvHD, and deliver translationally-relevant results for various research applications.
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Targeting Natural Killer Cell Activity with Humanized NSG IL-15 Mouse Model
The NEW cord blood CD34+ HSC humanized NSG-IL15 mouse enables efficacy research for compounds targeting human natural killer (NK) cell activity including antibody-dependent cellular cytotoxicity.
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A New Way to Study Cytokine Release Syndrome
In vivo CRS assays have the potential to simultaneously derisk and accelerate the process of bringing successful therapies to the patients who need them most.
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FAQs for Cryopreservation, Cryorecovery, and Breeding Services at JAX
Read on to find the answers to our most common questions regarding the cryopreservation, cryorecovery, and breeding services offered at JAX.
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JAX Guide: Assessing Antibody Pharmacokinetics Using the JAX FcRn Platform
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Common Laboratory Mouse Strains: A Beginner's Guide
This MiniCourse introduces inbred, outbred, and hybrid mouse strains and explains breeding schemes, nomenclature, genetic drift, finding phenotypic information, animal health and more.
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History and Development of the Mouse Model System
Learn the history behind the development of the mouse as a model system for human disease through landmark experiments, classical genetics and groundbreaking discoveries.
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Reproductive Biology of the Laboratory Mouse
Gain a basic understanding of laboratory mouse reproductive biology by examining basic anatomy, sex determination, the fertilization process, estrous cycle and more.
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CD34+ Hematopoietic Stem Cell Humanized Mice: The Basics
Frequently Asked Questions about CD34+ HSC Humanized Mice Humanized mouse models serve as an innovative and cost-effective platform to simulate trials, evaluate multiple drugs alone or in...
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The ABC’s of CAR T Cell Therapies
All that glitters… Cancer cells have found ingenious ways to evade the body’s immune system. These cells can shut off cytotoxic activity of anti-tumor T-cells, promoting their own...
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