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Immune Humanized Mice
JAX Presentation - Use of Humanized Mouse Models in Drug Development - Brian Soper, Ph.D.

JAX Presentation - Use of Humanized Mouse Models in Drug Development - Brian Soper, Ph.D.

Published Date April 7, 2025

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Advancing Immunotherapy Research with PBMC-Engrafted NSG* Models

Peripheral blood mononuclear cell (PBMC)-engrafted NSG mice serve as a robust model for studying T cell activation, immune modulation, and therapeutic intervention.
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Translatable Efficacy & Safety Testing of mAb, Bispecific, & CAR T Therapies

During this webinar, we discuss preclinical data showcasing efficacy and safety testing of immunotherapies in immune humanized mouse models.

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Use of Humanized Mouse Models in Drug Development - Voot Yin

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5 months ago
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During this webinar, we discuss preclinical data showcasing efficacy and safety testing of immunotherapies in immune humanized mouse models.

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about 2 years ago
SITC 2023 Comparison of Blinatumomab and Biosimilar CD19xCD3 BiTE responses in PBMC-Humanized Mice Used as a Preclinical Lymphoma Mouse Mode

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PEGS EU 2023 - Translational Humanized Models for Immunotherapy Drug Development

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CD34+ Hu-NSG-SGM3-IL15 Tech Sheet

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Evaluation of Safety and Efficacy of Antibody Therapies in Humanized Mice_Dr. James Keck

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A Novel PBMC Humanized Mouse Model_Dr. James Keck

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A humanized mouse model to study activity of cytotoxic and immunomodulatory human IgG - Dr. Anja Lux

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The Application of Humanized Mice in Manipulation of Myeloid Cells - Dr. Ali Roghanian

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The Next Generation of Humanized Mice for Translational Research - Dr. Michael Brehm

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Immunobiology of Human Immune Engrafted Platforms for Preclinical Drug Discovery - Dr. Brian Soper

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Humanized (NRG) Mice Supplemented with Dendritic Cells, Herpes Viruses or Lentiviral Vaccines Mount Antigen-Specific T and B Responses - Dr.

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Anja Lux, PhD, Friedrich Alexander University, speaking at The Jackson Laboratory EU Symposium. A humanized mouse model to study activity of cytotoxic and immunomodulatory human IgG antibodies.

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5 months ago
Humanized Mice: Application of Humanized Mice in Manipulation of Myeloid Cells

Ali Roghanian, PhD, University of Southampton speaking at The Jackson Laboratory EU Symposium. The application of humanized mice in manipulation of myeloid cells.

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over 2 years ago
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CD34+ Humanized Mice

Human cord blood-derived hematopoietic CD34+ stem cells. Validated: greater than 25% human CD45+ cells in peripheral blood. Humanized NSG variants (hu-CD34+). Infectious disease, gene therapy, cancer,

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