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AACR Annual Meeting 2026
In Vivo Evaluation of Autologous Anti-BCMA CAR-T Therapy in PBMC-humanized S15-DKO Mice Reveals Donor-specific Immune Responses

In Vivo Evaluation of Autologous Anti-BCMA CAR-T Therapy in PBMC-humanized S15-DKO Mice Reveals Donor-specific Immune Responses

Published Date April 22, 2026

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In vivo Lentiviral CAR-T Gene Delivery Demonstrates High Specificity and Potent anti-Tumor Activity in a Humanized B Cell Lymphoma Model
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A novel NSG-SGM3xIL15xDKO-based PBMC humanized mouse model to evaluate efficacy and cytokine release of immunotherapies

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3 days ago
Age-related transcriptional and alternative splicing changes in lung progenitor cells predisposing to immune dysfunction

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3 days ago
Improved humanization of peripheral blood mononuclear cells in NSG-SGM3xIL15xDKO (S15-DKO) over that of NSG-MHC I/II DKO mice for immune-onc

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3 days ago
Phone-based Portable Slide Digitization System for AI-Enabled Histopathology

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3 days ago
Inducing memory humoral responses using multiple vaccines in PBMC humanized mice

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3 days ago
Establishment of patient-derived lung epithelial progenitor lines as a foundation for autologous immune and tumor modeling

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3 days ago
In vivo Lentiviral CAR-T Gene Delivery Demonstrates High Specificity and Potent anti-Tumor Activity in a Humanized B Cell Lymphoma Model

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3 days ago
A novel NSG-SGM3xIL15xDKO-based PBMC humanized mouse model to evaluate efficacy and cytokine release of immunotherapies

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3 days ago
Robust Engraftment of Human γδ T Cells in Humanized NSG-SGM3-IL-15 x MHC I/II Double Knockout Mice For the Evaluation of γδ T Cell-based The

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17 days ago
AACR 2026 - Posters April 22

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2 months ago
Immune Cell Humanized Mice: CD34+ Hematopoietic Stem Cell Engrafted Mice

Charu Gupta, Ph.D., Senior Technical Information Scientist Key Takeaways:Diverse and Functional Immune Populations: HSC engraftment supports maturation of both adaptive and innate immune...

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2 months ago
Immune Cell Humanized Mouse Models: PBMC Engrafted Mice

Charu Gupta, Ph.D., Senior Technical Information ScientistKey PBMC Takeaways:Rapid engraftment: PBMCs engraft in 2-3 days with mature, human-protein expressing T cells.Human-relevant modeling:...

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8 months ago
HuPK™: A Humanized Platform for therapeutic antibody PK evaluation

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3 months ago
The Consequences of Sex Bias in Preclinical Research  Studies

Sam Eck, Ph.D. - Technical Information ScientistIntroduction: The Historical Context of Sex Bias In 1993, the NIH issued the Revitalization Act which for the first time required the inclusion of...

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2 months ago
PDX Models

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10 months ago
Comparing Immunodeficient Models for Cancer, Immunity, and Transplant Research

During this webinar, we will discuss the most widely used immunodeficient mouse models and important considerations for selecting the most appropriate model.

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3 months ago
Preclinical Therapeutic Antibody and Albumin-Conjugate Evaluation

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about 6 years ago
FcRn: Preclinical Therapeutic Antibody and Albumin-Conjugate Evaluation

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about 6 years ago
Oncology - Preclinical Models and Services

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Short Course on Experimental Models of Human Cancer

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Precision Oncology Clinical Education

Case-based modules about cancer biomarker testing and assessing targeted treatment options for cancer patients.

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