Misc. Flipbooks

Immuno-Safety Evaluation

HuPK™ A Platform for In Vivo Antibody PK Assessment

Humanized Mice For Immunotherapy Development

Upcoming Release of iPSC Lines

Evaluation of Safety and Efficacy of Antibody Therapies in Humanized Mice_Dr. James Keck

A Novel PBMC Humanized Mouse Model_Dr. James Keck

Evaluation of Safety and Efficacy of Antibody Therapies and Cell-based Therapies in Humanized Mice_Dr. James Keck

A humanized mouse model to study activity of cytotoxic and immunomodulatory human IgG - Dr. Anja Lux

The Application of Humanized Mice in Manipulation of Myeloid Cells - Dr. Ali Roghanian

Of Mice and Men - FcRn Biology and it's Implications in a Therapeutic Perspective

The Next Generation of Humanized Mice for Translational Research - Dr. Michael Brehm

Immunobiology of Human Immune Engrafted Platforms for Preclinical Drug Discovery - Dr. Brian Soper

Humanized (NRG) Mice Supplemented with Dendritic Cells, Herpes Viruses or Lentiviral Vaccines Mount Antigen-Specific T and B Responses - Dr.

A rapid, sensitive, and reproducible in vivo PBMC humanized murine model for determining therapeutic-related cytokine release syndrome

A study developed PBMC-engrafted NSG mouse models to assess CRS in vivo, demonstrating that these models are rapid, sensitive, and reproducible platforms for screening novel therapeutics for CRS.

JAX Handbook: Genetically Standardized Mice

Appendix 2: MHC H2 Haplotypes