Frequently Asked Questions about CD34+ HSC Humanized Mice Humanized mouse models serve as an innovative and cost-effective platform to simulate trials, evaluate multiple drugs alone or in...
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This video reviews mouse reproductive biology, focusing on optimizing the breeding productivity of research mouse colonies.
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This video reviews the basics of optogenetic mouse models and how researchers are using them to investigate neural circuitries underlying complex behaviors and neural diseases.
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What is in a name? From mouse strain nomenclature, you can determine genetic background, genetic modifications, who created the strain and who currently distributes it.
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In today's economic climate, research funding and vivarium space are becoming increasingly limited. As a result, investigators are challenged with managing their mouse colonies more efficiently.
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The revolutionary NOD scid gamma (NSG™) mouse model is used by investigators worldwide to advance research in cancer, infectious diseases and a wide array of immunological disorders.
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Did you know that CRISPR engineering can sometimes yield more than the allele you originally intended? Learn more about mosaicism, how to resolve it, and other CRISPR basics in this video.
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Success in the drug development pipeline depends on success in basic and preclinical research. Watch this video to learn about unique experimental design considerations for mouse-based research.
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Have you ever had to delay an experiment because you didn’t design your breeding scheme to produce enough knockout (KO) or control mice? Are you unsure of the most efficient way to set up your cross?
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Before undertaking a large study, it’s very beneficial to understand the biology of the model you are going to work with. This is particularly important when it comes to aging studies...
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Mouse nutrition is a complex and multifaceted topic, especially in preclinical research. Diets have an enormous impact on the overall health and welfare of mice, their development, and changes to...
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We’ve all heard the famous Ben Franklin quote, “if you fail to plan, you are planning to fail,” and any researcher knows, he was right. Planning is an essential part of any study: you plan for...
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More than 7,000 rare (or orphan) diseases have been described so far and affect over 350 million people worldwide. Unfortunately, less than 10% of these diseases have an approved treatment, and...
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