Utility Of Case Reports And JAX-CKB In Mitigating The Challenge Of Treating Patients With EGFR EXON 20 Insertions In Non-small Cell Lung Can
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Molecular pathologists need a comprehensive, evidence-based tool to cut through the complexity of cancer genomic profiles and deliver more actionable results for precision medicine.
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This whitepaper examines the constraints and challenges inherent in each CAR T study type and how to overcome them with in vivo studies using fully humanized mouse models.
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JAX NSG-MHC I/II KO mice readily engraft tumors and human PBMCs, have delayed GvHD, and deliver translationally-relevant results for various research applications.
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In vivo CRS assays have the potential to simultaneously derisk and accelerate the process of bringing successful therapies to the patients who need them most.
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