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AACR Annual Meeting 2023

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The Jackson Laboratory at AACR 2023
JAX Consulting Advisory Services

JAX Consulting Advisory Services

Published Date October 18, 2022

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Humanized NSG Mouse Models

CD34 and PBMC humanized NSG mice are powerful preclinical models for studying the actions of immuno-modulators, either alone or in combination with other treatments.
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Achieving Relevant Preclinical Characterization of CAR T Cell Therapies

This whitepaper examines the constraints and challenges inherent in each CAR T study type and how to overcome them with in vivo studies using fully humanized mouse models.

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Model Generation Services

Our team of subject matter experts will design your new mouse model based on your research goals.

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AACR 2022 Poster: Age-related Immunosenescence and Cancer Drug Toxicity and Efficacy in C57BL/6J Syngeneic Model

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JAX NSG-MHC I/II KO mice readily engraft tumors and human PBMCs, have delayed GvHD, and deliver translationally-relevant results for various research applications.

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A New Way to Study Cytokine Release Syndrome

In vivo CRS assays have the potential to simultaneously derisk and accelerate the process of bringing successful therapies to the patients who need them most.

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Targeting Natural Killer Cell Activity with Humanized NSG IL-15 Mouse Model

The NEW cord blood CD34+ HSC humanized NSG-IL15 mouse enables efficacy research for compounds targeting human natural killer (NK) cell activity including antibody-dependent cellular cytotoxicity.

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