During this JAX Tech Talk, Dr. Steven Rodriguez, Lab Head of the Rare & Neurological Diseases Therapeutic Area at Sanofi, discusses how his group uses iPSC models to understand disease biology.
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Watch this JAX Tech Talk to obtain expert guidance on using Cre-lox technology to develop your new model.
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Join us as we revisit the J:ARC Swiss Outbred model, a well-known outbred mouse model with numerous research applications, ranging from toxicity studies to recipient dams for in vitro fertilization.
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JAX technical information scientists Neeraj Tiwari and Peter Kelmenson discuss JAX research services including model selection, model generation and breeding.
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In this episode, we discuss considerations for working with HET3 mice, a comparison of HET3 to other models, and how this model is used to identify agents that extend lifespan and health span in mice.
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Learn the benefits of using the FcRn mouse model platform in characterizing the PK of your therapeutic, from the long half-life to the types of antibody therapeutics that can be screened.
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February 7, 2023 - In this episode, we discuss the importance of studying rare diseases and the critical preclinical steps leading to diagnosis and treatment development.
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We attended SfN 2022 to gather insights into how people within the scientific community use mouse models in their research. We talked to scientists across study areas such as neurodegenerative disease
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We attended SfN 2022 to gather insights into how people within the scientific community use mouse models in their research. We talked to scientists across study areas such as neurodegenerative disease
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December 6, 2022 In this episode of JAX Tech Talk, we discuss genotyping topics and misconceptions people have about our assays.
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November 8, 2022 - Congenic markers are a key tool for tracking cells in adoptive transfer and competitive bone marrow transplant experiments. But did you know that traditional strains harbor an artif
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Dr. Mark Cookson talks about the unique aspects of the collection of human isogenic iPSC lines and how it can benefit the wider scientific community in their shared quest to understand and fight ADRD.
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August 16, 2022 - In this episode, we have compiled some interesting questions that you have asked during past episodes. Revisit some of your questions and hear what our experts had to say.
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July 26, 2022 - In this episode, we consider methods to reduce bias in order to increase the translatability of your results to the clinic.
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June 28, 2022 - In this episode, we chat about making mouse models with large transgene inserts comparing different methodologies, and introducing Bxb1 integrase.
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This discussion focuses on preclinical efficacy and safety testing for novel antibody-based therapeutics.
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April 19, 2022 - Is your team involved in aging studies? In this episode, we dive into the advantages of aged HET3 mice from The Jackson Laboratory.
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April 5, 2022 - In the battle to fight cancer, one ingenious approach being pursued is chimeric antigen receptor (CAR) -based therapies. As cancer cells look to shut off the cytotoxic activity of anti
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March 15, 2022 - Is your team looking for more detailed and personalized support? In this episode, we will dive into all that our JAX Consulting and Advisory Services can offer your research program.
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March 1, 2022 - In this episode, the JAX Tech Talk Team welcomes Prabir Banerjee to discuss the JAX GvHD platform and its value in accelerating your preclinical research studies.
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