Frequently Asked Questions about CD34+ HSC Humanized Mice Humanized mouse models serve as an innovative and cost-effective platform to simulate trials, evaluate multiple drugs alone or in...
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What is in a name? From mouse strain nomenclature, you can determine genetic background, genetic modifications, who created the strain and who currently distributes it.
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In today's economic climate, research funding and vivarium space are becoming increasingly limited. As a result, investigators are challenged with managing their mouse colonies more efficiently.
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Cre-lox technology has quickly become one of the most widely used and versatile tools for genetically engineering mice for human disease modeling.
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Success in the drug development pipeline depends on success in basic and preclinical research. Watch this video to learn about unique experimental design considerations for mouse-based research.
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Do you need to generate new mouse models within 3-4 months instead of 1-1.5 years? Revolutionary CRISPR/Cas technology enables rapid, economical model generation through precise genome editing.
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Have you ever had to delay an experiment because you didn’t design your breeding scheme to produce enough knockout (KO) or control mice? Are you unsure of the most efficient way to set up your cross?
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All that glitters… Cancer cells have found ingenious ways to evade the body’s immune system. These cells can shut off cytotoxic activity of anti-tumor T-cells, promoting their own...
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Before undertaking a large study, it’s very beneficial to understand the biology of the model you are going to work with. This is particularly important when it comes to aging studies...
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What is NASH? Non-alcoholic fatty liver disease (NAFLD) is the most common form of chronic liver disease in the United States. Liver disease is often closely associated with obesity and...
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Mouse nutrition is a complex and multifaceted topic, especially in preclinical research. Diets have an enormous impact on the overall health and welfare of mice, their development, and changes to...
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The mouse is arguably the most widely used mammalian model in biomedical research. Their relatively small size, and both genetic and physiological similarity to humans, make mice a model organism...
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We’ve all heard the famous Ben Franklin quote, “if you fail to plan, you are planning to fail,” and any researcher knows, he was right. Planning is an essential part of any study: you plan for...
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