Mouse Models of Coronavirus Infection
In this webinar, we discuss upcoming and established strains in the JAX COVID-19 Model Portfolio, in the context of in vivo findings with SARS-CoV2 and related viruses.
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Infectious Disease
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Robust CAR-T Memory Formation and Function via Hematopoietic Stem Cell Delivery
Scott Kitchen, PH.D., Director of UCLA CFAR/JCCC Humanized Mouse Laboratory, presents at Humanized Mice Journal Club on October 26, 2021.
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JAX Tech Talk Episode 44: Let's Talk Grants for Genetic Background’s Impact on Translatability (Oct. 5, 2021)
October 5, 2021 - Is your treatment robust enough to "work" in different genetic backgrounds? Are your preclinical studies assessing translatability? In this episode, we will explore: how J:DO mice m
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Using mice to unravel the mysteries of COVID-19 disease
Nadia Rosenthal, Ph.D.
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The Importance of Testing Mice for COVID-19 Variants of Concern
Jim Fahey, Ph.D.
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Innovative and Novel Mouse Models for Studying Coronavirus Infection
Kaitlyn Gilland, Ph.D.
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MiceTech Talk Episode 36: Let's Talk Stress, Social Distancing, & Cage Density (May 11, 2021)
May 11, 2021- In this episode, we discuss the impact of caging configuration and environmental enrichment on the breeding and welfare of research mice.
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HuMouse models for the influence of genetic variation on the immune control of Epstein Barr
Christian Münz, Ph.D. - Professor and Co-director of the Institute of Experimental Immunology, University of Zürich, Switzerland Talk Title: Humanized mouse models for the influence of genetic variati
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Novel antibody tests reveal complexity of immune response to covid-19
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Exclusively from JAX: The COVID-19 Model Portfolio
We invite you to explore our comprehensive portfolio of COVID-19 models.
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Improving Translational Relevance with Humanized NSG™ Mice
Watch this video to learn the process of generating and characterizing “humanized” NSG™ (Hu-NSG™) mice and view data demonstrating preclinical research applications of these novel mouse models.
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Battling COVID-19; A New Model of Cytokine Release Syndrome
Under certain circumstances in patients, the human immune system can spin out of control and become highly toxic, resulting in cytokine release syndrome (CRS). CRS has been observed in certain...
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Top Tips on Selecting the “Best” Immunodeficient Mouse Model for Your Research
Immunodeficient mice are invaluable tools for immunology, infectious disease, oncology, hematopoietic, and regenerative medicine studies. They can serve as hosts for engraftment of mouse tumor...
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hACE2 Transgenic Model For COVID-19 Research
In this broadcast, Drs. Cat Lutz and Qiming Wang discuss the new hACE2 transgenic platform and answer questions from viewers.
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Modeling Infectious Disease in the Mouse: Challenges and Innovations
Watch this video to learn how JAX inbred mouse strains can be used to model infection as well as treatment and prevention of human infectious diseases.
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Battling HIV with CRISPR
The availability of combination antiretroviral therapies that inhibit HIV replication in cells and robustly reduce plasma viremia means that HIV infections are survivable rather than fatal....
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Humanized NSG™ Mice for HIV Research
Infection with HIV (human immunodeficiency virus) is the underlying cause of AIDS (acquired immunodeficiency syndrome). By 2014, nearly 37 million people worldwide were infected with HIV, and...
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Battling intracellular superbugs with antibody-antibiotic payload
Epidemiological Public Enemy No. 1 Commensal bacteria, such as Staphylococcus aureus, commonly populate skin and nasal passages, but can cause minor infections upon entering open wounds....
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An Update: Trends in Ebola Research
Although it has been over a year since the Ebola virus (EBOV) outbreak in West Africa, many survivors are still suffering from chronic virus infection as well as from the devastation of having...
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Tips & Tricks for Care of NSG Mice
The NSG™ mouse model is used by investigators worldwide to advance research in cancer, infectious diseases, and immunological disorders. Watch this video to learn how to care for NSG™ Mice.
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