During this webinar, we discuss the strengths and limitations of popular mouse models of human type 2 diabetes, obesity, and metabolic dysfunction-associated steatohepatitis (MASH).
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Watch this webinar to learn about the strengths and weaknesses of popular mouse models of human type 2 diabetes and obesity. webinar to learn about: • The benefits and limitations of some common
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Aged C57BL/6J mice represent a new dietary model for nonalcoholic steatohepatitis (NASH) that accounts for the known risk factor of age in the human disease.
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February 16, 2021 - In this episode, we talk about how to mimic human metabolism in mice and why temperature plays a critical role.
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This document highlights the key differences between aged and young C57BL/6J mice when it comes to NASH.
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Metabolic phenotypes expected from the JAX MSNASH/PcoJ Model
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In this seminar, we discuss the environmental factors that can influence diabetic phenotypes and can confound research results.
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Join Danielle Fontaine, Ph.D. and Andrew Schile, Ph.D. on Wednesday, August 26 as they discuss the NASH mouse models and what to consider when choosing the appropriate model for your study.
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An Interview with Professor Dave Serreze, Ph.D. and Jennifer Dwyer, Ph.D. on Type-1 Diabetes and Autoimmune diseases. Learn More Here: https://www.jax.org/explore-by-topic/diabetes/type-1-diabetes
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What is NASH? Non-alcoholic fatty liver disease (NAFLD) is the most common form of chronic liver disease in the United States. Liver disease is often...
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JAX has been distributing mouse models for type II diabetes (Non-insulin Dependent Diabetes; NIDD; T2D) since the 1960s, and today there are several models to choose from. Unfortunately, no...
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The hardest thing to see is what is in front of your eyes. – Johann Wolfgang von Goethe That Goethe quote was taped to one of my mentor’s microscopes and I thought of it when a recent article...
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Gain insights into the array of mouse models that can be used for nonalcoholic steatohepatitis (NASH) research and their translational relevance.
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A direct way to test whether a specific genomic variant plays a role in disease etiology and progression– namely to validate it as a potential target for therapy- is to introduce a corresponding...
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Before undertaking a large study, it’s very beneficial to understand the biology of the model you are going to work with. This is particularly important...
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In a previous blog post, we discussed some important Do’s and Don’ts of working with diabetic mouse models. Here we will discuss some of the most common questions we get from investigators who are...
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