During this presentation, we will compare strategies for immune humanization of NSG variants to support translatable preclinical immunology, and oncology research. researchers a powerful tool for cha
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In this presentation, we introduce The Jackson Laboratory’s most comprehensive immune humanized mouse platform to date: NSG- FLT3-IL15.
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We review strategies and mouse models used to develop highly promising therapeutic treatments using the body’s own immune system in the fight against cancer.
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January 16, 2024 - In this webinar, we discuss the most widely used immunodeficient mouse models and essential considerations for selecting the most appropriate model.
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In this webinar, we will introduce two new enhanced NSG models developed at The Jackson Laboratory: NSG-SGM3-IL15 and NSG-FLT3.
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Learn about the advantages of using genomic-based strategies in the fight against cancer
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Find out which tools and technologies are used by scientists to advance the field of cancer research, including sequencing, cell-based models of cancer, and mouse models of cancer.
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Leading this presentation is guest speaker Dr. Timothy Cripe from Nationwide Children’s Hospital and The Ohio State University.
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One of the major challenges oncologists are often faced with when managing precision cancer treatment is acquired drug resistance.
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The JAX Clinical Knowledgebase (CKB) is a relational database that contains data associated with cancer variants, tumor types, and therapies.
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Discover the fundamental properties of cancer cells and explore the genetic basis, inheritance, risk factors and prevention of this disease.
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The most common type of breast cancer is estrogen receptor-positive (ER+). ER+ tumors can be successfully treated with hormone therapy, but many tumors acquire endocrine resistance which limits treatm
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This on-demand webinar provides strategies for using PDX models in predictive preclinical research and an introduction to PDX models for immuno-oncology research.
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CRISPR/Cas9 can quickly generate new translational mouse models directly on the genetic background needed for your preclinical research. This saves valuable research time by reducing the need for...
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This whitepaper examines the constraints and challenges inherent in each CAR T study type and how to overcome them with in vivo studies using fully humanized mouse models.
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September 9, 2021 - Learn about unique experimental design considerations and critically important topics that affect the reproducibility of your In Vivo research studies.
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January 11, 2022 - In this episode, we will discuss using PBMC humanized NSG-MHC I/II DKO mice in preclinical research to develop and assess efficacy of human immuno-therapeutics.
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oin us as we talk with a JAX-CKB curator about what goes into the knowledgebase.
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Grace Berryhill, Ph.D. provides an overview of in vivo platforms being used to improve the translational relevance of cancer immunotherapies.
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