Advancing Immunotherapy Research with PBMC-Engrafted NSG* Models
Peripheral blood mononuclear cell (PBMC)-engrafted NSG mice serve as a robust model for studying T cell activation, immune modulation, and therapeutic intervention.
Watch Video
Peripheral blood mononuclear cell (PBMC)-engrafted NSG mice serve as a robust model for studying T cell activation, immune modulation, and therapeutic intervention.
Watch Video
Learn about JAX's enhanced innate immune models: the CD34+ engrafted NSG-FLT3 and NSG-FLT3-IL15 mice, presented by Michael Brehm, Ph.D., UMass Medical School.
Watch Video
During this webinar, we will discuss the most widely used immunodeficient mouse models and important considerations for selecting the most appropriate model.
Watch Video
Error - something went wrong!
Don't miss new content. Subscribe to our monthly newsletter, JAX Pulse!
Thank you!
In this episode, we delve into a publication that established a novel humanized mouse model of graft-versus-leukemia that better recapitulates the characteristics of AML relapse seen in patients.
Watch Video
During this presentation, we will compare strategies for immune humanization of NSG variants to support translatable preclinical immunology, and oncology research. researchers a powerful tool for cha
Watch Video
In this presentation, we introduce The Jackson Laboratory’s most comprehensive immune humanized mouse platform to date: NSG- FLT3-IL15.
Watch Video
We review strategies and mouse models used to develop highly promising therapeutic treatments using the body’s own immune system in the fight against cancer.
Learn More
Read Flipbook
In this webinar, we discuss the humanized FcRn platform, an effective tool that provides relevant PK data for candidate therapeutic antibodies and albumin-conjugated molecules.
Watch Video
In this webinar, we will introduce two new enhanced NSG models developed at The Jackson Laboratory: NSG-SGM3-IL15 and NSG-FLT3.
Watch Video
Read Flipbook
Read Flipbook
Read Flipbook
Bispecifics and CAR-T sequences
Watch Video
Read Flipbook
Read Flipbook
Simone Mester, PhD, Authera Biotech, speaking at The Jackson Laboratory EU Symposium. Of Mice and Men - FcRn biology and its implications in a therapeutic perspective.
Watch Video
Frank Lehmann, PhD, Cimeio Therapeutics, speaking at The Jackson Laboratory EU Symposium. Molecular shielding protects hematopoietic stem cells from antibody-mediated depletion.
Watch Video
Tomer Bronshtein, PhD speaking at The Jackson Laboratory EU Symposium. Preclinical to clinical development of next-generation mesenchymal cell therapy: from CAR-T induced CRS in humanized models to re
Watch Video
Read Flipbook
Loading More...