Exploring Cancer Research: Tools and Technologies
Learn More
Immuno-Oncology/Oncology
-
-
Leveraging Gene Therapy to Achieve Long-Term Continuous or Controllable Expression of Biotherapeutics
Leading this presentation is guest speaker Dr. Timothy Cripe from Nationwide Children’s Hospital and The Ohio State University.
Watch Video
-
JAX Clinical Knowledgebase - Identify Resistance Variants in Preclinical Drug Testing
One of the major challenges oncologists are often faced with when managing precision cancer treatment is acquired drug resistance.
Learn More
-
Immune-Humanized PDX Model-Estrogen-Independent, Hormone Receptor-Positive Metastatic Breast Cancer
The most common type of breast cancer is estrogen receptor-positive (ER+). ER+ tumors can be successfully treated with hormone therapy, but many tumors acquire endocrine resistance which limits treatm
Watch Video
-
Predictive Pre Clinical Oncology Studies Using Patient-Derived Xenograft Platforms
This on-demand webinar provides strategies for using PDX models in predictive preclinical research and an introduction to PDX models for immuno-oncology research.
Watch Video
-
How To Make Your New NSG Variant in a Fraction of the Time
CRISPR/Cas9 can quickly generate new translational mouse models directly on the genetic background needed for your preclinical research. This saves valuable research time by reducing the need for...
Learn More
-
Achieving Relevant Preclinical Characterization of CAR T Cell Therapies
This whitepaper examines the constraints and challenges inherent in each CAR T study type and how to overcome them with in vivo studies using fully humanized mouse models.
Read Flipbook
-
Designing Your In Vivo Studies
September 9, 2021 - Learn about unique experimental design considerations and critically important topics that affect the reproducibility of your In Vivo research studies.
Watch Video
-
JAX Tech Talk Episode 48: Developing Immunotherapies with Hu-NSG-MHC I/II DKO Mice (Jan. 11, 2022)
January 11, 2022 - In this episode, we will discuss using PBMC humanized NSG-MHC I/II DKO mice in preclinical research to develop and assess efficacy of human immuno-therapeutics.
Watch Video
-
Introduction to In Vivo Platforms for Cancer Immunotherapy
(recording date: 3/04/2021) Grace Berryhill, Ph.D. provides an overview of in vivo platforms being used to improve the translational relevance of cancer immunotherapies. Covered in this webinar are:
Watch Video
-
Human KIT+ Myeloid Cells Facilitate Visceral Metastasis By Melanoma
Chun Yu, Ph.D., Associate Research Scientist at The Jackson Laboratory speaks about Human KIT+ myeloid cells and how they facilitate visceral metastasis by melanoma.
Watch Video
-
JAX Tech Talk Episode 43: Let’s Talk Assessing Efficacy of GvHD Therapeutics (Sept. 14, 2021)
September 14, 2021 - In this episode, we discuss how the xenogeneic GvHD model in NSG mice aligns with your drug development pipeline.
Watch Video
-
GvHD Efficacy Study Fact Sheet
An example of study information provided when conducting a GvHD study with the Jackson Laboratory. This example shows Bispecific Antibodies in comparison with Abatacept.
Read Flipbook
-
JAX Tech Talk Episode 42: Let's Talk Oncology Solutions Using Advanced Cre-Lox Technology (Aug. 24, 2021)
Aug. 24, 2021 - In this episode, we apply the concepts of Cre-lox technology to control spatial and temporal gene expression and allow you to expand the types of questions you can answer in oncology.
Watch Video
-
Important Considerations for Generating Genetic Humanized Mouse Models
The term humanization is used, to much confusion, to mean several different things in mouse research. While broad in scope and technique, all humanized mouse models share a common goal – to better lev
Learn More
-
Understanding Natural Killer Cells in Cancer Immunotherapies
Basile Siewe, Ph.D. and Li-Chin (Lily) Yao, Ph.D., discuss cancer immunotherapies and specifically the role of NK cells in developing these therapies.
Watch Video
-
Genetically Diverse Mouse Models for Every Stage of the Research Pipeline
Mouse research is often performed in genetically-defined inbred mouse strains, where each mouse within a strain is virtually identical to one another.
Learn More
-
Modeling Chimeric Antigen Receptor (CARS) and T Cell Bispecific (TCB) Therapies in Mice
Modeling chimeric antigen receptor (CARS) and T cell bispecific (TCB) therapies in mice
Watch Video
-
JAX Antibody Development Summit - Jan Eckmann
Dr. Jan Eckmann, Group Leader Oncology Discovery Pharmacology at Roche, presents The Use of Humanized Mice in Antibody Drug Discovery as part of The Jackson Laboratory's Antibody Drug Development Summ
Watch Video
-
JAX Antibody Development Summit - James Keck
Dr. James Keck, Senior Director, Innovation and Product Development, The Jackson Laboratory, presents De-risking Therapeutic Antibody Preclinical Drug Development: Simultaneous Assessment of Efficacy
Watch Video
-
Loading More...
