Hear from experts on the many challenges and solutions in the preclinical drug development pipeline, how to choose the most translationally-relevant preclinical in vivo models to identify promising therapeutic candidates, and how large biopharmaceutical companies use humanized in vivo models as tools to de-risk their antibody drug development pipeline.
Dr. Dave Serreze, Professor, The Jackson Laboratory, presents Targeting Autoreactive B-cells Contributing to Type 1 Diabetes Development as part of The Jackson Laboratory's Antibody Drug Development S
Watch Video
Dr. Davide Schiavone, Head of Genetically Engineered Organisms Core at Alloy, presents Humanized Mouse Platforms for Therapeutic Antibody Discovery as part of The Jackson Laboratory's Antibody Drug De
Watch Video
Dr. Jan Terje Andersen, Professor, University of Oslo, presents FcRn as a Target for Engineering of Albumin-Based Biologics with Favorable In Vivo Properties as part of The Jackson Laboratory's Antibo
Watch Video
Dr. Geoff Hale, CEO, mAbsolve, presents Characterisation of Novel Antibodies Which are Completely Silenced with Respect to Fc Binding Function as part of The Jackson Laboratory's Antibody Drug Develo
Watch Video
Dr. Danyig Cai, Associate Director, Innovation & Product Development, The Jackson Laboratory, presents An In Vivo PBMC Humanized Mouse Model for Determining Immunotherapy Related Cytokine Release Synd
Watch Video
Dr. Delphine Valente, Head of Pharmacokinetics at Sanofi, presents Humanized FcRn Mice: a Promising Tool for Evaluating the Pharmacokinetics of Engineered Monoclonal and Multi Specific Antibodies as p
Watch Video
Dr. Jan Eckmann, Group Leader Oncology Discovery Pharmacology at Roche, presents The Use of Humanized Mice in Antibody Drug Discovery as part of The Jackson Laboratory's Antibody Drug Development Summ
Watch Video
Dr. James Keck, Senior Director, Innovation and Product Development, The Jackson Laboratory, presents De-risking Therapeutic Antibody Preclinical Drug Development: Simultaneous Assessment of Efficacy
Watch Video
