The term humanization is used, to much confusion, to mean several different things in mouse research. While broad in scope and technique, all humanized mouse models share a common goal – to better lev
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July 20, 2021 - In this episode, we discuss new approaches for expediting the development of mouse colonies that are sized for specific needs.
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Craft the ideal model with JAX's Model Generation Services to design and produce the genetically modified mouse model that is precisely what you need for your research.
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Join us this week for a conversation on Model Generation. We'll cover the basics on what it is, what types of models JAX can generate, critical factors in developing the right model for you, and much
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September 15, 2020 - In this episode, we discuss how to streamline mouse model generation.
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Watch Michael Brehm (University of Massachusetts Medical School) as he discusses highly immunodeficient NSG mouse models and their value in immuno-oncology and oncology research.
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Did you know that CRISPR engineering can sometimes yield more than the allele you originally intended? Learn more about mosaicism, how to resolve it, and other CRISPR basics in this video.
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Watch this video to get a refresher on the fundamentals of basic mouse genetics and learn some tricks from our experts to plan your next experiment better.
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A direct way to test whether a specific genomic variant plays a role in disease etiology and progression– namely to validate it as a potential target for therapy- is to introduce a corresponding...
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The trouble with ROS Approximately 6 million people worldwide suffer from primary inherited immunodeficiency diseases which pose a life-long challenge for those affected by them (Bousfiha et al.,...
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Whether you’re developing a novel inhibitor or determining whether a gene variant is a disease-driver, you might need a mouse model that doesn’t exist yet. CRISPR technology allows you to generate...
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Join is on Wednesday, September 9 for a follow up discussion about Model Generation. We will dive a little deeper into model generation, look into layering mutations, B6 to NODs, and more! For more in
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Read Flipbook
Read Flipbook
Read Flipbook
Check out this video for experience-based insights that can help you make decisions during your model development process.
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Watch this video to understand the potential of CRISPR/Cas to accelerate your research.
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