Partner with JAX-NYSCF
Read Flipbook
Latest Content
Welcome to our Hub! We hope you find something interesting to read, watch and share.
-
-
New JAX NSG portfolio strains support development of human NK cells in oncology models
IntroductionNatural killer (NK) cells occupy an intriguing niche between adaptive and innate immunity. Like cytotoxic T lymphocytes, they can recognize and kill infected or malignant cells and...
Learn More
-
Powering Discovery with JAX iPSC Models
Read Flipbook
-
Loading, please wait
Error - something went wrong!
Don't miss new content. Subscribe to our monthly newsletter, JAX Pulse!
Thank you!
-
Comparing Mouse Models for Metabolic Disease: Diabetes, Obesity, and MASH
Watch this webinar to learn how different mouse models capture different facets of human metabolic disease.
Watch Video
-
Guide to Using Cre-lox Technology to Generate Tissue-Specific Modifications
Watch this webinar to learn how to select appropriate combinations of Cre drivers and loxP-flanked alleles for tissue-specific effects.
Watch Video
-
Driving Better Therapeutic Antibodies with Next Generation Mouse Models
This webinar explores how to accelerate therapeutic antibody discovery by improving the quality and diversity of in vivo starting candidates using modern transgenic mouse platforms.
Watch Video
-
Cre Lox Breeding for Beginners, Part 2
In a previous post I discussed breeding Cre/lox mice to generate tissue-specific and inducible conditional knockout mouse strains. I would now like to continue the discussion of breeding Cre/lox...
Learn More
-
Cre Lox Breeding for Beginners, Part 1
Simply put, the Cre/lox system rocks. It is one of the most powerful tools in the mouse geneticist’s toolbox. Why? Well, it enables them to generate tissue-specific and inducible knockouts and...
Learn More
-
Insourcing or Outsourcing your Breeding Projects: Considerations and Advice for Making this Critical Decision
Many commercial and academic researchers have access to a vivarium and have not seriously considered using outside resources. Rising model complexity, tighter budgets, and shrinking vivarium...
Learn More
-
The Hallmarks of Aging – Key Mechanisms and Models in Neurobiology
Introduction: The History of “Hallmarks” in Biological ResearchLife science researchers worldwide are familiar with the publication series “The Hallmarks of Cancer”, initially laid out by Hanahan...
Learn More
-
Novel Mouse Models for Cancer Research
Read Flipbook
-
The Immunologist’s Toolbox: Workhorse Strains in the JAX Repository
Learn about JAX's collection of workhorse strains for tracking cells in adoptive transfer experiments, immunologically important cellular subsets, MHC Class I, II, and TCR-specific responses, & more.
Watch Video
-
Robust Engraftment of Human γδ T Cells in Humanized NSG-SGM3-IL-15 x MHC I/II Double Knockout Mice For the Evaluation of γδ T Cell-based The
Read Flipbook
-
Improved humanization of peripheral blood mononuclear cells in NSG-SGM3xIL15xDKO (S15-DKO) over that of NSG-MHC I/II DKO mice for immune-onc
Read Flipbook
-
Age-related transcriptional and alternative splicing changes in lung progenitor cells predisposing to immune dysfunction
Read Flipbook
-
Phone-based Portable Slide Digitization System for AI-Enabled Histopathology
Read Flipbook
-
Inducing memory humoral responses using multiple vaccines in PBMC humanized mice
Read Flipbook
-
Establishment of patient-derived lung epithelial progenitor lines as a foundation for autologous immune and tumor modeling
Read Flipbook
-
In vivo Lentiviral CAR-T Gene Delivery Demonstrates High Specificity and Potent anti-Tumor Activity in a Humanized B Cell Lymphoma Model
Read Flipbook
-
In Vivo Evaluation of Autologous Anti-BCMA CAR-T Therapy in PBMC-humanized S15-DKO Mice Reveals Donor-specific Immune Responses
Read Flipbook
-
Loading More...
