The Jackson Laboratory
Learn. Engage. Connect.
Cultural competency is defined as the ability to understand, appreciate and interact with people from a culture or belief systems different from one’s own (American Psychological Society 2015)....
(recording date 03/18/2021)
Grace Berryhill, Ph.D. speaks about patient-derived xenograft (PDX) mice, modeling the heterogeneity of human cancer, and conducting more translationally relevant cancer
(recording date: 3/04/2021)
Grace Berryhill, Ph.D. provides an overview of in vivo platforms being used to improve the translational relevance of cancer immunotherapies. Covered in this webinar are:
This scenario is more complicated than it may seem. With genomic tumor testing, a negative result is not always definitive. In some cases a genomic variant can be present but not detected by the...
Senior Manager and Technical Information Scientist, Brian Soper, Ph.D., discusses human immune system engrafted platforms and preclinical research.
Dr. Kaitlyn Gilland, Senior Technical Information Scientist, discusses working with aged C57BL/6J mice, study considerations, and preclinical testing.
November 16, 2021 - In this episode, we discuss methods and considerations for generating your translationally-relevant humanized mice.
Brian W. Soper, Ph.D. speaks about the efficacy and safety of therapeutics in immuno-modulatory induced cytokine release syndrome. Dr. Soper discusses human PBMC engraftment profiles; modeling human c
Scott Kitchen, PH.D., Director of UCLA CFAR/JCCC Humanized Mouse Laboratory, presents at Humanized Mice Journal Club on October 26, 2021.
With November designated as Family Health History month, clinicians are sure to have seen lots of messaging encouraging their patients to discuss family health history around the holiday table....
October 19, 2021 - Many research and preclinical programs require surgically modified mice. JAX Surgical Services provide a fast and easy way to obtain study-ready mice when needed. In this episode, w
October 5, 2021 - Is your treatment robust enough to "work" in different genetic backgrounds? Are your preclinical studies assessing translatability? In this episode, we will explore: how J:DO mice m
James Keck, Ph.D., Senior Director, Innovation and Product Development, at JAX speaks about a humanized preclinical in vivo system to predict the the immunotoxicity of antibody drug candidates.
Aaron Rose, Ph.D., Senior Study Director, In Vivo Services, The Jackson Laboratory speaks about testing the efficacy of immunomodulatory antibodies in humanized mice.
Greg Christianson, Study Director, In Vivo Services, The Jackson Laboratory
speaks about the use of human FcRn transgenic mouse models to select antibody therapeutic candidates with optimum pharmacoki
Brian Soper, Ph.D., Senior Manager, Technical Information Services, The Jackson Laboratory speaks about
human immune system engrafted mice and their role in human antibody-based drug development.
Chun Yu, Ph.D., Associate Research Scientist at The Jackson Laboratory speaks about Human KIT+ myeloid cells and how they facilitate visceral metastasis by melanoma.
September 14, 2021 - In this episode, we discuss how the xenogeneic GvHD model in NSG mice aligns with your drug development pipeline.
An example of study information provided when conducting a GvHD study with the Jackson Laboratory. This example shows Bispecific Antibodies in comparison with Abatacept.