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March 2, 2021 - Since launching our first mouse model for COVID-19 research in the summer of 2020, we have established a growing portfolio of over ten (10) COVID-19 models. In this episode, we will h
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Intro Why do millions of Americans and others around the world participate in consumer genomics? For many, testing provides a window into their innermost self, their genome, and a new way to...
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February 16, 2021 - In this episode, we talk about how to mimic human metabolism in mice and why temperature plays a critical role. We discuss the question, "Would studying mice at thermoneutrality
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We invite you to explore our comprehensive portfolio of COVID-19 models.
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For the first time ever, drug developers have the option to accurately assess immunotoxicity and drug efficacy in the same study utilizing a novel humanized platform.
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This document highlights the key differences between aged and young C57BL/6J mice when it comes to NASH.
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Happy Black and African American History Month from The Jackson Laboratory! According to The History Channel, Black History Month (also known as African American History Month) is an annual...
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February 2, 2021 - Many age-related diseases such as cancer, heart disease, and others are modelled in mice, prompting questions about how the life history of mice correlates with humans. In today's
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The NSG Humanized Mouse platform is an efficient way to test bispecific antibodies, including CD3 binding bispecific. This case study highlights our recent data.
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The NEW cord blood CD34+ HSC humanized NSG-IL15 mouse enables efficacy research for compounds targeting human natural killer (NK) cell activity including antibody-dependent cellular cytotoxicity.
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What makes a reliable genotyping gel? Is this funny smudge acceptable? We compare perfect (and passable) gels where you can get reliable genotype information with gels that need optimization.
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Assessing novel therapeutics that function to modulate the interaction between the human immune system and cancer cells requires advanced preclinical efficacy testing platforms. Immunologically...
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Genomic testing in healthcare is here to stay. Use of testing is increasing, not only in the traditional sense (think hereditary cancer or prenatal genetics), but also outside the doctor’s...
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Jan 5, 2021 - In today's episode we are going to answer the most frequently asked questions submitted to the JAX Technical Information Services team and will be taking questions live from you! We wi
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Metabolic phenotypes expected from the JAX MSNASH/PcoJ Model
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In this seminar, we discuss the environmental factors that can influence diabetic phenotypes and can confound research results.
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Would you like to minimize the resources you use to support your research mouse colonies? During this seminar, we discuss strategies to save cost and time by efficiently managing mouse colonies.
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Intro We’ve all felt this, to the point where I hesitate to say it out of fear of sounding trite. But, 2020 has been a year like no other we’ve known in recent memory; tumultuous in so many ways....
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Do you know how your genotyping assay works and what it is detecting? In this episode, we chat with JAX’s Genotyping group to walk through assay design basics.
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In this episode, we will be discussing what PDX models are, why they are considered more translatable, and examples of preclinical cancer studies conducted at JAX.
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