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Charu Gupta, Ph.D., Senior Technical Information ScientistKey PBMC Takeaways:Rapid engraftment: PBMCs engraft in 2-3 days with mature, human-protein expressing T cells.Human-relevant modeling:...
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Charu Gupta, Ph.D., Senior Technical Information ScientistKey Takeaways:Diverse and Functional Immune Populations: HSC engraftment supports maturation of both adaptive and innate immune...
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Simply put, the Cre/lox system rocks. It is one of the most powerful tools in the mouse geneticist’s toolbox. Why? Well, it enables them to generate tissue-specific and inducible knockouts and...
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The NntC57BL/6J mutation in the nicotinamide (NAD) nucleotide transhydrogenase (Nnt) gene is found exclusively in B6/J-derived mice and has not been detected in any other B6 substrains, including...
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This webinar provides key information about mouse strain nomenclature and genetic drift in the context of supporting research integrity.
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Learn about the MorPhiC Consortium and its initiative to generate a comprehensive catalog of molecular and cellular phenotypes for null alleles of every human protein-coding gene.
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As gene therapy continues to revolutionize modern medicine, the demand for reliable, translational, and ethically sound preclinical models has never been higher. In vivo gene delivery systems,...
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Cryopreservation is a powerful tool for colony management, protecting strains from loss while ensuring they remain available upon demand and at the scale needed (see IVF Speed Expansion...
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This document highlights the key differences between aged and young C57BL/6J mice when it comes to NASH.
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At The Jackson Laboratory (JAX), cryopreservation is a cornerstone of our research and colony management strategy. With decades of experience, we have optimized our cryopreservation protocols and...
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Introduction: The Historical Context of Sex Bias In 1993, the NIH issued the Revitalization Act which for the first time required the inclusion of women as participants in clinical drug trials....
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The Jackson Laboratory Contributes to Landmark Consensus Standards for Metabolic ResearchScientific progress depends on standardization. Just as consensus standards in genomics and metabolics...
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As the industry leader in laboratory mouse breeding, care, and colony management, we know how complex—and fragile—animal research can be. Maintaining animal colonies and developing experimental...
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In this webinar, we explore how Envision’s computer vision–based digital caging platform enables continuous, non-invasive monitoring of individual mice directly from the home cage.
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Learn about JAX's collection of workhorse strains for tracking cells in adoptive transfer experiments, immunologically important cellular subsets, MHC Class I, II, and TCR-specific responses, & more.
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