JAX Seminar 2024
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During this webinar, you will learn about the Cre-lox system. A widely used, modular technology that allows for spatially and temporally controlled genetic modifications.
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JAX Study Director Aaron Rose, Ph.D., explores how biological therapeutics are reshaping the drug development process and why humanized models are essential for advancing biologics programs.
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Join the JAX In Vivo Services team as they share insights from extensive neurobiology drug discovery studies conducted for both academic and commercial clients.
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This webinar is an exclusive behind-the-scenes look at JAX’s precise genetic engineering and high-throughput characterization of our human induced pluripotent stem cell (iPSC) lines.
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In this PubCast, we delve into Roche’s integration of humanized mice in their preclinical drug development pipeline to assess the safety and efficacy of their CD19-CD28 bispecific.
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If you’re gearing up to evaluate your drug candidates in clinically translatable, in vivo models, this webinar is for you.
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Join us as we discuss a collaborative effort between academia and a biopharmaceutical company, which utilized humanized mice to explore the role of mast cells in the melanoma tumor microenvironment.
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In this PubCast, we discuss a study from Yale University that employed humanized PBMC-NSG mice to model HIV and test the efficacy of two novel long-acting antiretroviral delivery systems. Resource
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In this presentation, we share a data-supported framework designed to trim costs, save time, and reduce the number of animals used for colony maintenance and cohort production.
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CD34 and PBMC humanized NSG mice are powerful preclinical models for studying the actions of immuno-modulators, either alone or in combination with other treatments.
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We review strategies and mouse models used to develop highly promising therapeutic treatments using the body’s own immune system in the fight against cancer.
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Limitations to scientific progress often arise not from a lack of curiosity or imagination, but rather from the tools and technologies available. While some research questions can be sufficiently...
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February 20, 2024 - During this presentation, we compare strategies for immune humanization of NSG variants to support translatable preclinical immunology and oncology research.
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In this webinar, we discuss cre-lox technology, a widely used and sophisticated tool to create general knockouts, conditional knockouts, and reporter strains.
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