Key Study Considerations for Preclinical Research with Aged Mouse Models
During this presentation, we discuss important experimental planning considerations to help ensure the efficiency and reproducibility of your aging studies.
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Latest Content
Welcome to our Hub! We hope you find something interesting to read, watch and share.
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Comparing Mouse Models for Metabolic Disease: Diabetes, Obesity, and MASH
During this webinar, we discuss the strengths and limitations of popular mouse models of human type 2 diabetes, obesity, and metabolic dysfunction-associated steatohepatitis (MASH).
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JAX Humanized Mice PubCast: IBD, Tregs, IL-2 + NSG mice
Learn about an immune humanized model of irritable bowel disease (IBD) used to investigate the mechanism of action and evaluate the therapeutic efficacy of interleukin-2 in treating ulcerative colitis
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Mouse Strains for the Study of Common Autoimmune Diseases
In this webinar, we discuss strains available from JAX that have yielded insight into lupus, psoriasis, Type I Diabetes, and Multiple Sclerosis.
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Strategies To Minimize Genetic Drift And Maximize Experimental Reproducibility In Mouse Research
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JAX Seminar 2024
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Guide to Using Cre-lox Technology to Generate Tissue-Specific Modifications
During this webinar, you will learn about the Cre-lox system. A widely used, modular technology that allows for spatially and temporally controlled genetic modifications.
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Biologics Drug Development Gets an Upgrade with Humanized Animal Models
JAX Study Director Aaron Rose, Ph.D., explores how biological therapeutics are reshaping the drug development process and why humanized models are essential for advancing biologics programs.
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Selecting and Using Mouse Models in Neurodevelopmental Drug Discovery
Join the JAX In Vivo Services team as they share insights from extensive neurobiology drug discovery studies conducted for both academic and commercial clients.
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Unlocking Insights with JAX's iPSCs: Rigorous Quality Control and Characterization to Accelerate Breakthroughs
This webinar is an exclusive behind-the-scenes look at JAX’s precise genetic engineering and high-throughput characterization of our human induced pluripotent stem cell (iPSC) lines.
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JAX Humanized Mice PubCast: CD19-CD28 Bispecific + FcRn mouse model to predict human PK
In this PubCast, we delve into Roche’s integration of humanized mice in their preclinical drug development pipeline to assess the safety and efficacy of their CD19-CD28 bispecific.
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Atlas Mice Developed by AbTherx
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HuPK Humanized FcRn Platform
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Humanized Mice for Immunotherapy Development
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Acute Immunotoxicity Evaluation Studies
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How-to Guide for Selecting Xenografts & Mouse Models for Preclinical Cancer Research
If you’re gearing up to evaluate your drug candidates in clinically translatable, in vivo models, this webinar is for you.
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JAX Humanized Mice PubCast: Mast cells & Anti-PD-1 Therapy (Apr. 3, 2024)
Join us as we discuss a collaborative effort between academia and a biopharmaceutical company, which utilized humanized mice to explore the role of mast cells in the melanoma tumor microenvironment.
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Poster: Translational Humanized Models for Immunotherapy Drug Development | Immuno 2024
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JAX Humanized Mice PubCast: HIV-1 in Humanized Mice (Mar. 14, 2024)
In this PubCast, we discuss a study from Yale University that employed humanized PBMC-NSG mice to model HIV and test the efficacy of two novel long-acting antiretroviral delivery systems. Resource
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What Do Experimental Mice Really Cost?
In this presentation, we share a data-supported framework designed to trim costs, save time, and reduce the number of animals used for colony maintenance and cohort production.
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