The Jackson Laboratory

JAX Humanized Mice PubCast: Acute Myeloid Leukemia + NSG-MHC I/II DKO Mice

In this episode, we delve into a publication that established a novel humanized mouse model of graft-versus-leukemia that better recapitulates the characteristics of AML relapse seen in patients.

Support Reproducibility & the 3R’s with Effective Mouse Colony Management

During this webinar, we share advice on maintaining mouse colonies in alignment with the principles of the 3Rs: replacement, reduction, and refinement.

Navigating Mouse Nomenclature and Genetic Drift: Best Practices for Research Integrity

During this webinar, we provide key information about mouse strain nomenclature and genetic drift in the context of supporting research integrity.

Humanized Mice for the Assessment of the Safety of Immunotherapies

Next-Generation Humanized Models for the Preclinical Development of Therapeutic Antibodies

Using the HuPK™ Platform to Predict the PK of Candidate Therapeutic Antibodies

Atlas™ Mice Provide a New and Differentiated Toolset for Rapid Generation of Developable Human Therapeutic Antibodies

New Directions for Therapeutic Antibody Formats: An Overview of Development Trends and the Current Clinical Pipeline

Comparing Immune-Humanized Mouse Platforms for Preclinical Applications

During this presentation, we will compare strategies for immune humanization of NSG variants to support translatable preclinical immunology, and oncology research. researchers a powerful tool for cha