Targeting Natural Killer Cell Activity with Humanized NSG(TM)-Il15 Mouse Model
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Latest Content
Welcome to our Hub! We hope you find something interesting to read, watch and share.
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Financial considerations of genomic tumor testing
Maria is a 70-year old woman in your practice with a new diagnosis of advanced non-small cell lung cancer (NSCLC). You plan to test a biopsy specimen for a handful of recommended genes, but what...
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JAX Innovation: Where We See Preclinical Research Going
Join us for the next episode of JAXLive! On Wednesday, September 16th, we will be speaking with Danielle Fontaine, Ph.D. and Michael Ellis, Ph.D. as they discuss innovation when it comes to generating
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Model Generation Part 2: Building Complex Models and Embracing Genetic Diversity
Join is on Wednesday, September 9 for a follow up discussion about Model Generation. We will dive a little deeper into model generation, look into layering mutations, B6 to NODs, and more! For more in
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JAXLive! Model Generation Part 1: An Introduction
Join us this week for a conversation on Model Generation. We'll cover the basics on what it is, what types of models JAX can generate, critical factors in developing the right model for you, and much
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Key Considerations for NASH Models
Join Danielle Fontaine, Ph.D. and Andrew Schile, Ph.D. on Wednesday, August 26 as they discuss the NASH mouse models and what to consider when choosing the appropriate model for your study.
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An In Vivo Model to Evaluate Donor-Dependent Cytokine Release
Dr. Kyle Draheim discusses developing a translational humanized mouse model for preclinical assessment of efficacy and CRS related to immuno-oncology therapies single agents and in combination.
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MiceTech Talk Episode 19: Let's Talk Common Conditions of B6 Mice (Sept. 22, 2020)
In this episode, we will share with you some tips and facts about B6 mice conditions such as alopecia, dermatitis, malocclusion and hydrocephalus and how to manage them.
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MiceTech Talk Episode 18: Let's Talk Knockin Mouse Models (Sept. 15, 2020)
Join us as we discuss how to streamline mouse model generation.
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MiceTech Talk Episode 17: Let's Talk Tamoxifen (Sept. 8, 2020)
We are going to talk about the do's, the don'ts, and the most frequently asked questions about tamoxifen.
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MiceTech Talk Episode 16: Let's Talk Genotyping (September 1, 2020)
Join as we discuss topics such as getting started with genotyping, selecting and using genotyping protocols, and interpreting and troubleshooting genotyping results.
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Using RNA sequencing and other technologies to aid in variant interpretation
Malik is your 6-year-old patient with autism and global developmental delay. DNA testing did not identify a pathogenic variant (mutation) using a multi-gene neurology panel. However, a variant of...
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JAX Diversity Outbred Mice: A Genetically Diverse Mouse for a Diverse Human Population
Most traditional laboratory mouse strains were established by taking a mouse with unique characteristics and inbreeding it to produce a mouse population that is composed of virtually identical...
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Part 2 of a 3-part Humanized Mouse Series: What to Consider When Humanizing an Immunodeficient Mouse
Join Rick Huntress and Natalie Hurlen, Ph.D. on Wednesday, August 12 as they discuss humanizing immunodeficient mice. Learn more here: https://resources.jax.org/jax-blog/working-with-humanized-nsg-mic
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Responding to the Pandemic: What is Next for Post-COVID-19 Research?
Rob Taft, PhD, Senior Services Program Manager at The Jackson Laboratory (JAX) speaks with GEN about how to keep research resilient post-COVID-19.
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Part 1 of a 3-part HuMouse Series: Exploring JAX NSG Platform: Specialized Humanized Mouse Models
Join Rick Huntress and Aaron Rose, Ph.D. today as they discuss the ways that JAX can support custom humanization projects, including the NBSGW or NSG-Kit (026622). Learn More at: https://www.jax.org/j
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Working with Humanized NSG mice: In-sourced or Out-sourced
The term “humanized” mouse can mean many things to many people, but we’ll define it as a mouse that harbors engrafted human tissue or cells, such as immune cells. Here are some helpful tips.
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Modeling a Population: An Overview of JAX Diversity Outbred Mice
Join us today for a conversation on Diversity Outbred Mice with Kelly Brackett, Ph.D. and Elizabeth Axton, Ph.D. -- Want to learn more? Read our latest blog: https://www.jax.org/news-and-insights/2019
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Why humanized mice?
You may have noticed that the latest biomedical breakthroughs are utilizing more and more humanized mice. But, what is a humanized mouse and why would scientists want to utilize this type of...
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MiceTech Talk Episode 14: Let's Talk Cre-lox (Aug. 18, 2020)
In this episode, we will cover tips to help you generate your Cre-lox models more easily
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