Exome Testing For Diagnosis
Watch this video for an overview of the clinical indications for exome testing, associated benefits, risks and limitations, and interpreting results.
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Learn. Engage. Connect.
Watch this video for an overview of the clinical indications for exome testing, associated benefits, risks and limitations, and interpreting results.
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This MiniCourse introduces core concepts of genetically diverse mouse models and their applicability for common translational research studies.
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The dose selection for first-in-human (FIH) clinical trials relies on data obtained by a combination of in vitro and in vivo studies designed to evaluate the efficacy, toxicity, and stability of...
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This on-demand webinar provides strategies for using PDX models in predictive preclinical research and an introduction to PDX models for immuno-oncology research.
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April 19, 2022 - Is your team involved in aging studies? In this episode, we dive into the advantages of aged HET3 mice from The Jackson Laboratory.
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CRISPR/Cas9 can quickly generate new translational mouse models directly on the genetic background needed for your preclinical research. This saves valuable research time by reducing the need for...
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Technical Information Services Manager, Brian Soper, Ph.D., explores recent advances in CAR mediated strategies for human immuno-oncology. Recorded on 4-7-22
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Introduction Since the first chimeric antigen receptor (CAR) T cell therapy received FDA approval in 2017, this promising immunotherapy modality has only continued to gather momentum. Existing CAR...
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This whitepaper examines the constraints and challenges inherent in each CAR T study type and how to overcome them with in vivo studies using fully humanized mouse models.
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It’s been long recognized that aging is the single biggest risk factor for cancer and that age impacts treatment response. Research is urgently needed to develop a mechanistic understanding of the...
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April 5, 2022 - In the battle to fight cancer, one ingenious approach being pursued is chimeric antigen receptor (CAR) -based therapies. As cancer cells look to shut off the cytotoxic activity of anti
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JAX NSG-MHC I/II KO mice readily engraft tumors and human PBMCs, have delayed GvHD, and deliver translationally-relevant results for various research applications.
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A glimpse at the wide range of platforms and services JAX offers to help move you from drug discovery to IND filing.
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Review JAX’s CRS evaluation capabilities and see how a CRS study can help move your CAR T therapeutic into the clinic faster, safer, and more confidently.
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March 15, 2022 - Is your team looking for more detailed and personalized support? In this episode, we will dive into all that our JAX Consulting and Advisory Services can offer your research program.
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March 1, 2022 - In this episode, the JAX Tech Talk Team welcomes Prabir Banerjee to discuss the JAX GvHD platform and its value in accelerating your preclinical research studies.
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Just last week, the Food and Drug Administration (FDA) published recommendations to drug developers and researchers urging them to consider alternatives to non-human primates (NHPs) in general...
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September 9, 2021 - Learn about unique experimental design considerations and critically important topics that affect the reproducibility of your In Vivo research studies.
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February 15, 2022 - With new advances being unraveled in the world of CAR T therapies, Team JAX Tech Talk discusses the latest advancements JAX has developed to support drug developers in the field.
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Although many mammals have immune systems that share important characteristics with humans, certain immune cell types and phenomena are unique to us. As a result, it has been difficult to design...
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