Old Age and Diet Together in Mice Represent a Unique Model of Human NASH
Aged C57BL/6J mice represent a new dietary model for nonalcoholic steatohepatitis (NASH) that accounts for the known risk factor of age in the human disease.
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Latest Content
Welcome to our Hub! We hope you find something interesting to read, watch and share.
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Understanding Natural Killer Cells in Cancer Immunotherapies
Basile Siewe, Ph.D. and Li-Chin (Lily) Yao, Ph.D., discuss cancer immunotherapies and specifically the role of NK cells in developing these therapies.
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Wearables, clinical data and COVID-19
Like one in five Americans, I wear a watch that also tracks several health-related statistics through the day. It tells me how well I slept, how many steps I took, how high my heart rate got...
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JAX Tech Talk, Episode 40: Let’s Talk Aligning Mice Generation with Preclinical Studies (20Jul2021)
July 20, 2021 - Having the right number and genotype of mice, just when you need them, can be as challenging as designing the perfect research or drug efficacy study itself. In today’s episode, we wi
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Chen. K Chai Memorial Lecture
Moving From Hammer to Nail: Genomics and Health Outcomes in 2021 Katrina Armstrong, M.D., Massachusetts General Hospital
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Thomas H. Roderick Memorial Lecture
Mapping the Human Gastrointestinal Tract Through Space and Time Sarah Teichmann, F.Med.Sci, FRS, Wellcome Sanger Institute
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Genetically Diverse Mouse Models for Every Stage of the Research Pipeline
Mouse research is often performed in genetically-defined inbred mouse strains, where each mouse within a strain is virtually identical to one another.
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JAX Tech Talk, Episode 39: Let's Talk JAX Swiss Outbred Mice (29-Jun-2021)
June 29, 2021 - In this episode, we will discuss the new JAX Swiss Outbred mouse model also known as J:ARC. We will talk about how this strain is maintained using the Poiley method of rotational non-s
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JAX Antibody Development Summit - Jan Eckmann
Dr. Jan Eckmann, Group Leader Oncology Discovery Pharmacology at Roche, presents The Use of Humanized Mice in Antibody Drug Discovery as part of The Jackson Laboratory's Antibody Drug Development Summ
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JAX Antibody Development Summit - James Keck
Dr. James Keck, Senior Director, Innovation and Product Development, The Jackson Laboratory, presents De-risking Therapeutic Antibody Preclinical Drug Development: Simultaneous Assessment of Efficacy
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JAX Antibody Development Summit - Delphine Valente
Dr. Delphine Valente, Head of Pharmacokinetics at Sanofi, presents Humanized FcRn Mice: a Promising Tool for Evaluating the Pharmacokinetics of Engineered Monoclonal and Multi Specific Antibodies as p
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JAX Antibody Development Summit - Jan Terje Andersen
Dr. Jan Terje Andersen, Professor, University of Oslo, presents FcRn as a Target for Engineering of Albumin-Based Biologics with Favorable In Vivo Properties as part of The Jackson Laboratory's Antibo
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JAX Antibody Development Summit - Geoff Hale
Dr. Geoff Hale, CEO, mAbsolve, presents Characterisation of Novel Antibodies Which are Completely Silenced with Respect to Fc Binding Function as part of The Jackson Laboratory's Antibody Drug Develo
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JAX Antibody Development Summit - Danying Cai
Dr. Danyig Cai, Associate Director, Innovation & Product Development, The Jackson Laboratory, presents An In Vivo PBMC Humanized Mouse Model for Determining Immunotherapy Related Cytokine Release Synd
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JAX Antibody Development Summit - Davide Schiavone
Dr. Davide Schiavone, Head of Genetically Engineered Organisms Core at Alloy, presents Humanized Mouse Platforms for Therapeutic Antibody Discovery as part of The Jackson Laboratory's Antibody Drug De
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JAX Antibody Development Summit - Dave Serreze
Dr. Dave Serreze, Professor, The Jackson Laboratory, presents Targeting Autoreactive B-cells Contributing to Type 1 Diabetes Development as part of The Jackson Laboratory's Antibody Drug Development S
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Pride Month Q&A with JAX Employees
Pride Month celebrates the LGBTQ+ community, encompassing lesbian, gay, bisexual, transgender, queer, intersex, asexual, and other identities. Pride month is celebrated in June to honor the 1969...
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C9Orf72 Tech Spec Sheet
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JAX Tech Talk, Episode 38: Let's Talk Pharmacokinetics for Antibody Development (15-June-2021)
June 15, 2021 - One step in preparing novel therapeutics for the clinic is measuring the PK of your molecule. In this episode, we’ll share some tools to give you robust, translationally relevant half-
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Episode 37: Let's Talk How to Test if Your Drug Induces a Cytokine Storm (25May2021)
May 25, 2021 - Cytokine Release Syndrome (CRS) occurs when the immune system is over-activated, triggered by factors including the administration of many cancer immunotherapies. Drug developers of CAR
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