Envision 5.0_A Platform Built for Home Cage Research
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Latest Content
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High-Throughput Genome Editing and Quality Control of Human iPSC Lines for Large Scale Disease Modeling
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Automated iPSC-derived Islet Organoids Platform for Population-scale Modeling of Type 2 Diabetes
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A Scalable and Reversible Strategy to Knock Out Gene Function in Human Induced Pluripotent Stem Cells
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Development Approach to Modeling Intracranial Germ Cell Tumors Using Human Pluripotent Stem Cells
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Natural Genetic Variation Reveals Loci Controling Differentiation Propensity and Lineage Specification in Mouse Embryonic Stem Cells
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Diverse Embryonic Stem Cells Reveal Coevolved Genome Regulatory Incompatibilities Affecting Viability and Fertility
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Mapping RPE-to-Photoreceptor Programming for Stem Cell Therapy
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High-Throughput Expansion and Banking of iPSC Lines Using the JAX-NYSCF Automated Platform
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Diet-induced Obese Tg32 (hFcRN) : a New Platform for PK Analysis of Anti-obesity Peptide-Fc Based and Antibody Therapeutics
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Advancing Translational Relevance in Preclinical Mouse Models for Alzheimer’s Disease
Watch this webinar for guidance on the informed selection of in vivo mouse models for the preclinical evaluation of therapeutic candidates for Alzheimer’s disease.
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Guide to Using Cre-lox Technology to Generate Tissue-Specific Modifications
Watch this webinar to learn how to select appropriate combinations of Cre drivers and loxP-flanked alleles for tissue-specific effects.
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An Introduction to iPSCs: Applications, Models, and Best Practices
In this webinar, we’ll cover the basics of iPSCs, showcase real-world research applications, and discuss the biological questions these models help answer.
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The JAX-NYSCF Global Stem Cell Array®️
Automated platform to generate high-quality induced iPSC lines and differentiate them into diverse, disease-relevant cell types. Advanced capabilities for efficient, reproducible research.
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An Advanced PBMC-Humanized NSG-S15-DKO Mouse Model for Comprehensive Evaluation of Immunotherapeutics
What You'll Learn:PBMC models enable in vivo human immune system studiesDelayed GvHD supports longer, more flexible study windowsNSG-S15-DKO shows:Enhanced multi-lineage engraftment (T, NK,...
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S15-DKO: New Platform for Engraftment of Human PBMC Supporting Multilineage Immune Cells, Low GvHD
Learn about the S15‑DKO strain (NSG-NSG‑MHC I/II DKO × NSG‑SGM3‑IL15), which supports broader human immune cell engraftment (T, B/plasma, NK, cDC, macrophages, γδ T cells) without acute xGvHD.
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Home Sweet Home: Leveraging Continuous Home-Cage Monitoring to Improve Science and Animal Welfare
Learn how the Behavioral Phenotyping Core at Seattle Children’s Research Institute expanded its capabilities with the integration of the Allentown Discovery IVC Rack powered by The Jackson Laboratory.
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Partner with JAX-NYSCF
Learn more about the JAX-NYSCF partnership to accelerate cures for the major diseases of our time through stem cell research, from large iPSC cohorts for specific disease areas to developing...
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New JAX NSG portfolio strains support development of human NK cells in oncology models
IntroductionNatural killer (NK) cells occupy an intriguing niche between adaptive and innate immunity. Like cytotoxic T lymphocytes, they can recognize and kill infected or malignant cells and...
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Powering Discovery with JAX iPSC Models
View highlights and comparison of JAX genetically engineered isogenic iPSC and donor-derived, disease-specific iPSC lines.
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