Evidence-Based Selection of the Starting Dose in First-in-Human Clinical Trials Using Humanized Mouse Models
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Case Studies
This Stream includes all of our Case Studies Flipbooks
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In Vivo Evaluation of Bispecific T-Cell Engager Efficacy and Safety
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Case Study: Evaluation of the Anti-Tumor Efficacy of a Bispecific in Two Novel In Vivo Systems
The NSG Humanized Mouse platform is an efficient way to test bispecific antibodies, including CD3 binding bispecific. This case study highlights our recent data.
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Targeting Natural Killer Cell Activity with Humanized NSG IL-15 Mouse Model
The NEW cord blood CD34+ HSC humanized NSG-IL15 mouse enables efficacy research for compounds targeting human natural killer (NK) cell activity including antibody-dependent cellular cytotoxicity.
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Zygote Editing of a NOD Mouse to Better Understand the Mechanism of Diabetes
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Proficiency with Larger Knockins
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