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ISSCR 2026
Development Approach to Modeling Intracranial Germ Cell Tumors Using Human Pluripotent Stem Cells

Development Approach to Modeling Intracranial Germ Cell Tumors Using Human Pluripotent Stem Cells

Published Date July 8, 2026

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A Scalable and Reversible Strategy to Knock Out Gene Function in Human Induced Pluripotent Stem Cells
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Mapping RPE-to-Photoreceptor Programming for Stem Cell Therapy

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High-Throughput Genome Editing and Quality Control of Human iPSC Lines for Large Scale Disease Modeling

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Automated iPSC-derived Islet Organoids Platform for Population-scale Modeling of Type 2 Diabetes

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A Scalable and Reversible Strategy to Knock Out Gene Function in Human Induced Pluripotent Stem Cells

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Natural Genetic Variation Reveals Loci Controling Differentiation Propensity and Lineage Specification in Mouse Embryonic Stem Cells

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Diverse Embryonic Stem Cells Reveal Coevolved Genome Regulatory Incompatibilities Affecting Viability and Fertility

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23 days ago
The JAX-NYSCF Global Stem Cell Array®️

Automated platform to generate high-quality induced iPSC lines and differentiate them into diverse, disease-relevant cell types. Advanced capabilities for efficient, reproducible research.

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about 1 month ago
Partner with JAX-NYSCF

Learn more about the JAX-NYSCF partnership to accelerate cures for the major diseases of our time through stem cell research, from large iPSC cohorts for specific disease areas to developing...

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about 1 month ago
Powering Discovery with JAX iPSC Models

View highlights and comparison of JAX genetically engineered isogenic iPSC and donor-derived, disease-specific iPSC lines.

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8 months ago
Engineered vs. Patient-Derived iPSCs: Strengths, Limitations, and Applications

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about 1 year ago
Why Clonal iPSC Lines Are Essential: Building a Foundation for Reliable and Reproducible Research

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11 months ago
Defining a Reference iPSC Line: Criteria, Context, and the Case of KOLF2.1J

In the field of stem cell research, the quest to define a “reference” induced pluripotent stem cell (iPSC) line is ongoing and nuanced. As we deepen our understanding of human biology, one thing...

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10 months ago
From iPSCs to Microglia in Record Time: A Xeno-Free, Tet-Inducible Differentiation Protocol Using KOLF2.1J.

In this webinar, Dr. Oliveira will introduce JAX’s new Tet-inducible neuron and microglia human induced pluripotent stem cell (hiPSCs) lines.

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4 months ago
Tools with a Mission: Using Disease Models to Find a Treatment for PURA Syndrome

This webinar explores the urgent need for innovative models and highlights JAX’s development of iPSC lines to advance understanding of PURA syndrome and enable drug discovery.

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5 months ago
MorPhiC: Decoding Human Protein-Coding Gene Function at Scale in iPSC-Derived Multicellular Systems

Learn about the MorPhiC Consortium and its initiative to generate a comprehensive catalog of molecular and cellular phenotypes for null alleles of every human protein-coding gene.

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6 months ago
JAX Tech Talk Episode 68: Let’s Talk iPSC Disease Models as a Tool in Drug Discovery (Nov. 7, 2023)

During this JAX Tech Talk, Dr. Steven Rodriguez, Lab Head of the Rare & Neurological Diseases Therapeutic Area at Sanofi, discusses how his group uses iPSC models to understand disease biology.

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6 months ago
JAX Tech Talk Episode 59: Let’s Talk iPSCs and Their Value in Tackling Neurodegenerative Diseases (Sep. 20, 2022)

Dr. Mark Cookson talks about the unique aspects of the collection of human isogenic iPSC lines and how it can benefit the wider scientific community in their shared quest to understand and fight ADRD.

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