Human Immune System Engrafted Mice and Their Role in Human Antibody-Based Drug Development

September 29, 2021

Brian Soper, Ph.D., Senior Manager, Technical Information Services, The Jackson Laboratory speaks about human immune system engrafted mice and their role in human antibody-based drug development.

Human Immune System Engrafted Mice and Their Role in Human Antibody-Based Drug Development

A New Way to Study Cytokine Release Syndrome

Poster: A Humanized In Vivo System to Predict Antibody-induced Cytokine Release Syndrome

A Humanized Preclinical in Vivo System to Predict the Immunotoxicity of Antibody Drug Candidates

CRS: FAQs

Choosing the Appropriate Humanized FcRn Mouse Model to Test the Pharmacokinetics of Antibody Therapeutics

The Humanized FcRn Platform: An Essential Tool for Preclinical PK Assessment of Therapeutic Antibody Candidates

JAX Guide: Assessing Antibody Pharmacokinetics Using the JAX FcRn Platform

Poster: Choosing the Appropriate Immune System- Humanized Mouse Model for Immuno-Modulatory Therapies

Mode of Action of TCell Bispecific Antibodies and their Combinations with Checkpoint Inhibitors

Testing the Efficacy of Immuno-Modulatory Antibodies in Humanized Mice

The ABC’s of CAR T Cell Therapies