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Comparing Immune-Humanized Mouse Platforms for Preclinical Applications

The highly immunodeficient NSG™ platform enables precise in vivo modeling of human immune responses. This platform offers researchers a powerful tool for characterizing and validating immune-modulating therapeutics. During this presentation, we compare strategies for immune humanization of NSG variants to support translatable preclinical immunology and oncology research.

Join us to learn about:

  • HSC and PBMC immune cell humanization techniques using the NSG platform
  • The impact of host selection and genetic modifications (e.g., growth factors and cytokines) on engrafted immune phenotypes
  • Novel NSG variants that offer improved human innate immune cell development