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A MHC Class I & II Deficient Platform Humanized with PBMCs

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JAX NSG-MHC I/II KO mice readily engraft tumors and human PBMCs, have delayed GvHD, and deliver translationally-relevant results for various research applications.

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JAX NSG-MHC I/II KO mice accept engraftment of tumors and human PBMCs, exhibit delayed GvHD, and deliver translationally-relevant results for a wide range of research applications, including exploratory immunology studies and preclinical therapeutic evaluation.