Designing and validating mouse models for the study of Amyotrophic Lateral Sclerosis (ALS) and other neuromuscular diseases presents a unique set of challenges. The JAX In Vivo Pharmacology Services team has validated and routinely employs five robust ALS mouse models to support drug discovery.
Join us to review:
- phenotypic characteristics and considerations for selecting therapeutically relevant ALS models
- sample study designs and experimental readouts to evaluate the efficacy of candidate molecules to treat ALS