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ABCs of Antibody Discovery: Leveraging Biological Foundations and Modern Platforms

Published Date

The shift toward antibody therapeutics represents a landmark evolution in medicine: moving beyond the broad systemic effects of traditional chemotherapy and small molecule drugs toward a paradigm of high-precision targeting and harnessing the power of the patient’s immune response. By leveraging a significantly longer half-life, binding exclusively to specific antigens, and triggering a wide array of downstream effects, antibody therapeutics promise a more effective approach while reducing the likelihood of off-target toxicity compared to traditional chemotherapy.

In this webinar, you will learn:

  • The fundamentals of the lymphatic system, B cell physiology, and how the body naturally generates antibody diversity
  • Mechanism of action of antibody neutralization, opsonization, complement activation, and Antibody-Dependent Cellular Cytotoxicity
  • The therapeutic antibody discovery workflow
  • Benefits and considerations of current industry platforms for therapeutic antibody production, such as phage display, hybridoma production, and transgenic mouse models