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Episode 37: Let's Talk How to Test if Your Drug Induces a Cytokine Storm (25May2021)

May 25, 2021 - Cytokine Release Syndrome (CRS) occurs when the immune system is over-activated, triggered by factors including the administration of many cancer immunotherapies. Drug developers of CAR T cells or bispecific antibodies often don’t know that a cytokine storm may jeopardize the patient’s life until a drug recipient experiences devastating CRS-induced side effects. In today’s episode, we will discuss how JAX created a unique platform to help predict CRS, addressing this critical challenge earlier in the drug development process. Helpful Resources What is Cytokine Release Syndrome? JAX's new Cytokine Release Syndrome Evaluation Study A new humanized model for the prediction of CRS in vivo