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Optimizing Experimental Design Using Aged Mouse Models

Published Date

Aging research is inherently time and resource intensive, making strategic planning essential for generating reliable and interpretable results. This presentation will address critical elements of experimental design that support the efficiency, rigor, and reproducibility of aging studies.

Topics will include:

  • Aging mouse study design - foundational principles for structuring long-term aging experiments
  • Sources of variation in aging cohorts - factors that influence outcomes in lifespan and health-span studies
  • Lifecycle-dependent phenotype changes - how age-related shifts in physiology and behavior affect study planning
  • Aging phenotypes in C57BL/6J and HET3 mice - well-documented characteristics of two of the most used aging models