For mouse-based research investigating new cures for human diseases, one sex is far too often selected over the other. This is sometimes done with sound scientific justification, but omitting sex as a biological variable has several consequences. Single sex studies can lead to skewed research, translatability issues, or flawed conclusions and raise concerns regarding ethical practices and the 3Rs.
During this presentation, you will learn more about:
- Reasons why male or female mice are sometimes preferred
- The scientific impact sex bias has on multiple biological disciplines
- The significant effect of sex bias on animal welfare
- 3Rs guidelines and recommendations to eliminate sex bias in preclinical studies