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Enhanced Development of Human Innate Immunity in Humanized Mice

Published Date

Presented by Michael Brehm, Ph.D., Associate Professor, Diabetes Center of Excellence, Program in Molecular Medicine, UMass Medical School.

Learn about JAX's enhanced innate immune models: the CD34+ engrafted NSG-FLT3 and NSG-FLT3-IL15 mice, powerful tools for immuno-oncology and autoimmune studies.

The webinar covers:

  • The kinetics of human immune system development in CD34+ HSC-engrafted NSG-FLT3 mice
  • The function of human innate immune systems in HSC-engrafted NSG-FLT3 mice in tumor engraftment contexts
  • Next-generation innate immune system models (including FLT3-IL15 mice)