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Human HSC & PBMC Platforms for In Vivo Immune Modulatory Drug Discovery

Published Date

JAX offers advanced humanized platforms that support in vivo human immune cell development and function, helping researchers uncover cellular and molecular interactions needed to model both efficacy and safety prior to clinical trials.

In this webinar, we explore:

  • Key differences between peripheral blood mononuclear cell (PBMC) and CD34+ stem cell engraftment
  • Applications for PBMC and CD34+ engrafted mice in immuno-oncology
  • Comparison of NSG* and NSG-MHC I/II DKO models for studying immune responses

*NSG is a registered trademark in the USA and other countries