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JAX Tech Talk Episode 43: Let’s Talk Assessing Efficacy of GvHD Therapeutics (Sept. 14, 2021)

September 14, 2021 - Graft versus host disease (GvHD) is a common complication following the transplantation of hematopoietic cells. Acute GvHD is associated with damage to the skin, liver, and gastrointestinal tract, while chronic GvHD can resemble autoimmune syndromes. The xenogeneic GvHD model in NSG mice provides the unique opportunity to test therapeutic approaches in an in vivo scenario. In this episode, we will discuss how this platform aligns with your drug development pipeline!

Helpful Resources:

Graft vs Host Disease (GvHD): Preclinical Efficacy Services 

Investigating Immunomodulation: Examining GvHD Using Humanized NSG™ Mice from JAX 

Frequently Asked NSG™ Questions